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| Applications | Tested Dilution | Publications |
|---|---|---|
Flow Cytometry (Flow) |
Assay-dependent | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Mouse |
Host/Isotype |
Hamster / IgG |
Class |
Monoclonal |
Type |
Antibody |
Clone |
2F1 |
Immunogen |
Immunogen information and sequence are proprietary |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.5 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
PBS |
Contains |
0.09% sodium azide |
Storage conditions |
2-8°C |
KLRG1 (Killer cell lectin-like receptor G1, MAFA, 2F1-Ag) is a homodimeric member of the lectin-like type 2 transmembrane receptor family whose members contain characteristic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their cytoplasmic domains. These ITIMs interact with the SH2 domains of protein phosphatases such as SHP-1. KLRG1 is an inhibitory receptor that is expressed on natural killer (NK) cells and certain T cells. NK cells are involved in the lysis of tumor cells and virus-infected cells, and mediate humoral and cell-mediated immune responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Killer cell lectin-like receptor subfamily G member 1; Mast cell function-associated antigen 2F1; natural killer cell receptor
Gene Aliases: 2F1-Ag; Klrg1; MAFA; MAFA-L
UniProt ID: (Mouse) O88713
Entrez Gene ID: (Mouse) 50928
Molecular Function:
transmembrane signal receptor
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