Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (N
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Importin alpha P1; Importin subunit alpha-1; importin subunit alpha-2; importin-alpha-P1; karyopherin (importin) alpha 2; karyopherin alpha 2 (RAG cohort 1, importin alpha 1); Karyopherin subunit alpha-2; m-importin-alpha-P1; nuclear import protein; Pendulin; Pore targeting complex 58 kDa subunit; PTAC58; RAG cohort protein 1; SRP1-alpha
Gene Aliases: 2410044B12Rik; importin; IPOA1; KPNA2; PTAC58; QIP2; RCH1; SRP1; SRP1-alpha; SRP1alpha
Molecular Function: transfer/carrier protein