Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
OriGene
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:2500-1:5000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:150 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:100 | - |
Miscellaneous PubMed (Misc) |
- | View 2 publications 2 publications |
| Product Specifications | |
|---|---|
Species Reactivity |
Dog, Human, Rat |
Published species |
Not Applicable |
Host/Isotype |
Mouse / IgG2b |
Class |
Monoclonal |
Type |
Antibody |
Clone |
OTI1B12 |
Immunogen |
Human recombinant protein fragment corresponding to amino acids 91-381 of human CK8 produced in E.coli. |
Conjugate |
Unconjugated |
Form |
liquid |
Concentration |
1 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
PBS with 1% BSA, 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
Cytokeratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. Cutokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C CY K2C8; CK 8; CK-8; Cytokeratin endo A; Cytokeratin-8; hard keratin; K-8; K8; keratin 8, type II; keratin complex 2, basic, gene 8; Keratin, type II cytoskeletal 8; Keratin-8; Type-II keratin Kb8
Gene Aliases: CARD2; CK-8; CK8; CYK8; CYKER; K2C8; K8; KO; Krt2-8; KRT8
UniProt ID: (Human) P05787, (Rat) Q10758
Entrez Gene ID: (Dog) 486513, (Human) 3856, (Rat) 25626
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support
