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Abnova
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Sequence of this protein is as follows: MKATVIRHGE TLRRTKEEIN ELNRMIQRLT AEVENAKCQN SKLEAAVAQS EQQGEAALSD ARCKLAELEG ALQKAKQDMA CLIREYQEVM NSKLGLDIEI ATYRRLLEGE EQRLCEGIGA VNVCVSSSRG GVVCGDLCVS GSRPVTGSVC SAPCNGNVAV STGLCAPCGQ LNTTCGGGSC GVGSCGISSL GVGSCGSSCR KC
Cell culture grade monoclonal antibodies are obtained by purifying "hybridoma culture medium" which completely eliminates any contamination of mice. They have high affinity, high purity, and no contamination.
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ghHb1; ghHKb1; Hair keratin K2.9; hard keratin, type II, 1; K81; keratin 81, type II; Keratin, hair, basic, 1; Keratin, type II cuticular Hb1; Keratin-81; Metastatic lymph node 137 gene protein; MLN 137; Type II hair keratin Hb1; Type-II keratin Kb21
Gene Aliases: ghHkb1; Hb-1; HB1; hHAKB2-1; KRT81; KRTHB1; MLN137
UniProt ID: (Human) Q14533
Entrez Gene ID: (Human) 3887
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