|Tested species reactivity||Virus|
|Published species reactivity||Not Applicable|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Purified recombinant fragment of KSHV K8 alpha expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1/500 - 1/2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
MA5-14768 targets KSHV K8a in IHC and WB applications and shows reactivity with Virus samples.
The MA5-14768 immunogen is purified recombinant fragment of KSHV K8a expressed in E. Coli.
Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi and quote;s sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman and quote;s disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. KSHV K8 and K8.1 open reading frames are juxtaposed and span from nucleotide (nt) 74850 to 76695 of the virus genome. A K8 pre-mRNA overlaps the entire K8.1 coding region, and alternative splicing of KSHV K8 and K8.1 pre-mRNAs each produces three isoforms (α, β, and γ) of the mRNAs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Not Applicable||Not Cited||
Systematic analysis of a xenograft mice model for KSHV+ primary effusion lymphoma (PEL).
MA5-14768 was used in western blot to characterize a xenograft mice model for KSHV+ primary effusion lymphoma (PEL)
|Dai L,Trillo-Tinoco J,Bai L,Kang B,Xu Z,Wen X,Del Valle L,Qin Z||PloS one (9:null)||2014|