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Product Details
PA5-53416
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human KCNA4
Conjugate
Unconjugated
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2642909
Product Specific Information
Immunogen sequence: NFNYFYHRET ENEEQTQLTQ NAVSCPYLPS NLLKKFRSST SSSLGDKSEY LEMEEGVKES LCAKEEKCQG KGDDSETDKN NCSNAKAVET DV
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 99%.
Target Information
Potassium voltage-gated channel subfamily A member 4, also known as Kv1.4 or PCN2, is a protein that in humans is encoded by the KCNA4 gene. This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. It is mapped to 11p14.1. KCNA4 belongs to the A-type potassium current class, the members of which may be important in the regulation of the fast repolarizing phase of action potentials in heart and thus may influence the duration of cardiac action potential. KCNA4 also contributes to the cardiac transient outward potassium current (Ito1), the main contributing current to the repolarizing phase 1 of the cardiac action potential. This gene has been shown to interact with DLG4, KCNA2 and DLG1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cardiac potassium channel; fetal skeletal muscle potassium channel; HPCN2; potassium channel 2; potassium channel, voltage gated shaker related subfamily A, member 4; Potassium voltage-gated channel subfamily A member 4; rapidly inactivating potassium channel; shaker-related potassium channel Kv1.4; type A potassium channel; Voltage-gated K(+) channel HuKII; Voltage-gated potassium channel HBK4; Voltage-gated potassium channel HK1; Voltage-gated potassium channel subunit Kv1.4
Gene Aliases: HBK4; HK1; HPCN2; HUKII; KCNA4; KCNA4L; KCNA8; KV1.4; PCN2
UniProt ID: (Human) P22459
Entrez Gene ID: (Human) 3739
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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