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KV3.4 (KCNC4) Antibody (PA5-90618) in WB
Western blot analysis of KV3.4 (KCNC4) in extracts of various cell lines. Samples were incubated with KV3.4 (KCNC4) Polyclonal antibody (Product # PA5-90618) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
Product Details
PA5-90618
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 490-538 of human KCNC4 (NP_0049692)
Conjugate
Form
Liquid
Concentration
1.36 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2806149
Product Specific Information
Immunogen sequence: KKRKKHVPRP AQLESPMYCK SEETSPRDST CSDTSPPARE EGMIERKRA; Positive Samples: U-87MG, Mouse brain; Cellular Location: Membrane, Multi-pass membrane protein
Target Information
The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Several transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: K+ channel subunit; KSHIIIC; MGC126818; potassium channel, voltage gated Shaw related subfamily C, member 4; Potassium voltage-gated channel subfamily C member 4; potassium voltage-gated channel, Shaw-related subfamily, member 4; Voltage-gated potassium channel KCNC4; Voltage-gated potassium channel subunit Kv3.4
Gene Aliases: AI850292; C1orf30; HKSHIIIC; KCNC4; Kcr2-4; KSHIIIC; KV3.4
UniProt ID: (Human) Q03721, (Mouse) Q8R1C0
Entrez Gene ID: (Human) 3749, (Mouse) 99738
Performance Guarantee
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