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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 87 and 260 of Human KLK10|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-30131 targets Kallikrein 10 in WB applications and shows reactivity with Human samples.
The PA5-30131 immunogen is recombinant protein fragment corresponding to a region within amino acids 87 and 260 of Human KLK10.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
1; breast normal epithelial cell associated serine protease; kallikrein 10; kallikrein 10 protein 1; kallikrein 10 protein 12; kallikrein 10 protein 13; kallikrein 10 protein 2; kallikrein 10 protein 3; kallikrein 10 protein 4; kallikrein 10 protein 5; kallikrein 10 protein 7; kallikrein 10 protein 8; kallikrein 10 protein 9; kallikrein-10; kallikrein-related peptidase 10; NES1; normal epithelial cell-specific 1; protease; protease serine-like 1; protease, serine-like, 1; PRSSL1; serine-like
KLK10; NES1; PRSSL1