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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Residues 68-82 of the 35 kDa human hippostasin/Kallikrein 11protein.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Hippostatin, also known as Kallikrein 11, is a kallikrein-like serine protease, which has two alternatively spliced isoforms, brain-type and prostate-type. Hippostatin plays a role in the prostate, including reproductive and/or tumorigenic functions. Elevated srum levels of hK11 were found in 70% of women with ovarian cancer and in 60% of men with prostate cancer. Analysis of the KLK11 biomarker in serum may aid in the diagnosis and monitoring of ovarian and prostatic carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
hippostasin; hK11; kallikrein 11; kallikrein-related peptidase 11; serine protease 20; trypsin-like protease
KLK11; PRSS20; TLSP; UNQ649/PRO1279