|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic Peptide: I(262) R K Y E T Q Q Q K W L K G P Q(277)|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500|
PA1-4239 detects Kallikrein-13 from human samples.
PA1-4239 has been successfully used in Western blot procedures.
PA1-4239 immunizing peptide corresponds to amino acid residues 262-277 from human Kallikrein-13.
Kallikreins are a subgroup of serine proteases and are implicated in carcinogenesis. The novel KLK gene, KLK-L4 (also known as KLK-13) is expressed in a variety of tissues including prostate, salivary gland, breast, and testis. Its expression is regulated by steroid hormones in breast cancer cell lines may be involved in the pathogenesis and/or progression of breast cancer.