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Product Details
PA5-78134
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human Kallikrein 6. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.88 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2735974
Product Specific Information
Positive Control: Target recombinant protein^M
^M
Predicted Reactivity: Dog (88%), Rhesus Monkey (98%), Bovine (83%)^M
^M
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Kallikreins, including Kallikrein 6, are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The KLK6 enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: kallikrein 6; kallikrein 7; Kallikrein-6; Kallikrein6; MGC9355; Neurosin; Protease M; Serine protease 18; Serine protease 9; SP59; Zyme
Gene Aliases: Bssp; hK6; KLK6; Klk7; PRSS18; PRSS9; SP59
UniProt ID: (Human) Q92876
Entrez Gene ID: (Human) 5653
central nervous system development
response to wounding
regulation of neuron projection development
protein processing
protein autoprocessing
collagen catabolic process
tissue regeneration
hormone metabolic process
myelination
amyloid precursor protein metabolic process
regulation of cell differentiation
positive regulation of G-protein coupled receptor protein signaling pathway
neuron death
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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