PA1-642 detects kinesin 5A from mouse, human, and bovine samples. This antibody is specific for kinesin 5A and does not detect other kinesin isotypes.
PA1-642 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~110 kDa protein representing kinesin 5A from mouse neuronal cell lysate and human retinal extracts.
The PA1-642 immunizing peptide corresponds to amino acid residues 1007-1027 from mouse kinesin 5A. This sequence is completely conserved in human. This peptide (Cat. # PEP-197) is available for use in neutralization and control experiments.
This gene encodes a member of the kinesin family of proteins. Members of this family are part of a multisubunit complex that functions as a microtubule motor in intracellular organelle transport. Mutations in this gene cause autosomal dominant spastic paraplegia 10.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: KIF5A variant protein; Kinesin heavy chain isoform 5A; Kinesin heavy chain neuron-specific 1; kinesin, heavy chain, neuron-specific; Neuronal kinesin heavy chain; NKHC
Gene Aliases: D10Bwg0738e; D12S1889; Khc; Kiaa4086; Kif5; KIF5A; Kns; mKIAA4086; MY050; NKHC; NKHC1; SPG10