This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human CD208/DC-LAMP.
Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses (summary by de Saint-Vis et al., 1998 [PubMed 9768752]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD208; DC LAMP; DC-lysosome-associated membrane glycoprotein; LAMP-3; lysosomal-associated membrane protein 3; Lysosome-associated membrane glycoprotein 3; Protein TSC403
Gene Aliases: CD208; DC LAMP; DC-LAMP; DCLAMP; LAMP; LAMP-3; LAMP3; TSC403
UniProt ID: (Human) Q9UQV4
Entrez Gene ID: (Human) 27074
Molecular Function: membrane trafficking regulatory protein