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Product Details
H00204219-M02
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
6C12
Immunogen
LASS3 (NP_849164, 57 a.a. approximately 134 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: EKFVASPLAK SFGIKETVRK VTPNTVLENF FKHSTRQPLQ TDIYGLAKKC NLTERQVERW FRSRRNQERP SRLKKFQE
Target Information
LASS3 (Longevity Assurance homolog 3) is a member of a highly conserved family of proteins from yeast to humans which are involved in the synthesis of ceramide. Overproduction of LASS3 appears to results in increases in several ceramide species, with some preference toward those having middle to long chain fatty acid acyl-CoAs. Also appears to have (dihydro)ceramide synthesis activity. LASS3 expression appears to be limited almost solely to the testis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ceramide synthase 3; CerS3; Dihydroceramide synthase 3; LAG1 homolog, ceramide synthase 3; LAG1 longevity assurance homolog 3; longevity assurance homolog 3; MGC27091; related to TRH3; Sphingosine N-acyltransferase CERS3; Ultra-long-chain ceramide synthase CERS3; Very-long-chain ceramide synthase CERS3
Gene Aliases: 4930550L11Rik; ARCI9; CERS3; Gm488; LASS3; RGD1564356; T3L
UniProt ID: (Human) Q8IU89, (Mouse) Q1A3B0
Entrez Gene ID: (Human) 204219, (Rat) 499174, (Mouse) 545975
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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