Endotoxin level < 24 EU/mg.
This antibody reacts highly specific with mouse natural and recombinant LBP. The antibody is a type II antibody blocking the LPS binding to CD14.
The MA1-40030 immunogen is mouse natural and recombinant LBP.
MA1-40030 detects LBP from mouse samples.
MA1-40030 has been successfully used in ELISA, Functional Assays and Western blot applications.
The LBP protein is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). Finally, this gene is found on chromosome 20, immediately downstream of the BPI gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: LBP; Lipopolysaccharide-binding protein
Gene Aliases: Bpifd2; Lbp; Ly88
UniProt ID: (Mouse) Q61805
Entrez Gene ID: (Mouse) 16803