Perlecan is an extracellular matrix proteoglycan. It has a large core protein of 400-450 kDa and is often produced with heparan sulfate side chains. Perlecan is found in basement membranes where it contributes to the permeability characteristics, serves as a substrate for vascular cells and binds growth factors involved in vascular remodelling.
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Protein Aliases: [Phosphatase 2A protein]-leucine-carboxy methyltransferase 1; CGI-68; LCMT; LCMT1; Leucine carboxyl methyltransferase 1; Phosphatase 2A protein-leucine-carboxy methyltransferase 1; PP2A methyltransferase
Gene Aliases: AL033290; Lcmt; LCMT-1; Lcmt1
UniProt ID: (Rat) Q6P4Z6