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This gene encodes an enzyme which catalyzes the reversible conversion of lactate and pyruvate, and NAD and NADH, in the glycolytic pathway. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on the X chromosome and on chromosome. Multiple alternatively spliced variants, encoding the same protein, have been identified.
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Protein Aliases: epididymis secretory protein Li 281; L-lactate dehydrogenase B chain; lactate dehydrogenase H chain; Lactate dehydrogenease B; LDH heart subunit; LDH-B; LDH-H; LDHH; Renal carcinoma antigen NY-REN-46; testicular secretory protein Li 25
Gene Aliases: AI790582; H-Ldh; HEL-S-281; Ldh-2; LDH-B; LDH-H; Ldh2; LDHB; LDHBD; TRG-5
UniProt ID: (Human) P07195, (Rat) P42123, (Mouse) P16125
Entrez Gene ID: (Human) 3945, (Rat) 24534, (Mouse) 16832
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