This Antibody was verified by Knockout to ensure that the antibody binds to the antigen stated.
It is not recommended to aliquot this antibody.
This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DKFZp586H0919; FLJ46390; HGNC:6551; HMG Binding Domain; LEF-1; lymphoid enhancer binding factor 1 short isoform; Lymphoid enhancer-binding factor 1; OTTHUMP00000219736; OTTHUMP00000219737; T cell-specific transcription factor 1-alpha; TCF1-alpha
Gene Aliases: 3000002B05; AI451430; LEF-1; LEF1; TCF10; TCF1ALPHA; TCF7L3