A suggested positive control for this product is Bosc23 cells transfected with neurosin.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Bssp; hK6; kallikrein 6; Kallikrein-6; Klk7; MGC9355; NEUROSIN; Protease M; PRSS18; PRSS9; Serine protease 18; Serine protease 9; SP59; ZYME
Gene Aliases: Bssp; hK6; KLK6; Klk7; PRSS18; PRSS9; SP59
UniProt ID: (Human) Q92876
Entrez Gene ID: (Human) 5653