|Tested species reactivity||Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues 1-50 of mouse fragilis.|
|Storage buffer||PBS with 0.05% BSA|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||0.5-2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Suggested positive control: NIH-3T3 whole cell lysates.
Fragilis is an IFN-induced transmembrane protein that belongs to the highly conserved fragilis protein family. It consists of an N-terminal signal sequence, 2 putative transmembrane domains, 3 potential phosphorylation sites and C-terminal Leucine-zipper. It is expressed in early embryos and nascent primordial germ cells and is associated with Germ cell specification and development. It is cell surface protein and might be important in mediating interactions amongst germ cells and their surrounding neighbours. It is also suggested that it might be involved in anti-proliferative signaling and homotypic cell adhesion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.