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Product Details
CF504527
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:1,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:150 | - |
Immunocytochemistry (ICC/IF) |
1:100 | - |
Flow Cytometry (Flow) |
1:100 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Mouse / IgG1 |
Class |
Monoclonal |
Type |
Antibody |
Clone |
OTI2D5 |
Immunogen |
Human recombinant protein fragment corresponding to amino acids 100-362 of human LHX1 produced in HEK293T cell. |
Conjugate |
Unconjugated |
Form |
lyophilized |
Concentration |
1 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 8% trehalose |
Contains |
no preservative |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and be involved in control of differentiation and development of neural and lymphoid cells. A similar protein in mice is an essential regulator of the vertebrate head organizer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hLim-1; Homeobox protein Lim-1; LHX-1; LIM homeobox protein 1; LIM/homeobox protein Lhx1; MGC126723; MGC138141
Gene Aliases: LHX1; LIM-1; LIM1
UniProt ID: (Human) P48742
Entrez Gene ID: (Human) 3975
Molecular Function:
helix-turn-helix transcription factor
homeodomain transcription factor
DNA-binding transcription factor
gene-specific transcriptional regulator
urogenital system development
ureteric bud development
branching involved in ureteric bud morphogenesis
gastrulation with mouth forming second
ectoderm formation
endoderm formation
kidney development
transcription from RNA polymerase II promoter
cell-cell signaling
pattern specification process
nervous system development
motor neuron axon guidance
anatomical structure morphogenesis
post-embryonic development
embryonic pattern specification
organ morphogenesis
anterior/posterior axis specification
anterior/posterior pattern specification
dorsal/ventral pattern formation
regulation of gene expression
retina layer formation
ventral spinal cord development
spinal cord association neuron differentiation
telencephalon development
cerebellum development
cerebellar Purkinje cell differentiation
forebrain regionalization
cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation
somite rostral/caudal axis specification
metanephric part of ureteric bud development
oviduct epithelium development
uterine epithelium development
nephric duct elongation
horizontal cell localization
positive regulation of embryonic development
cellular response to fibroblast growth factor stimulus
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
anatomical structure formation involved in morphogenesis
embryonic viscerocranium morphogenesis
pronephros development
embryonic retina morphogenesis in camera-type eye
uterus development
oviduct development
cervix development
vagina development
head development
epithelium development
paramesonephric duct development
comma-shaped body morphogenesis
S-shaped body morphogenesis
renal vesicle morphogenesis
mesonephric duct development
nephric duct morphogenesis
metanephric glomerulus development
metanephric comma-shaped body morphogenesis
metanephric renal vesicle morphogenesis
metanephric S-shaped body morphogenesis
primitive streak formation
positive regulation of branching involved in ureteric bud morphogenesis
lateral motor column neuron migration
positive regulation of gastrulation
positive regulation of anterior head development
positive regulation of nephron tubule epithelial cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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