Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
CF810327
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
OTI5C7
Immunogen
Human recombinant protein fragment corresponding to amino acids 220-406 of human LHX2 produced in E.coli.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator. The protein can recapitulate or rescue phenotypes in Drosophila caused by a related protein, suggesting conservation of function during evolution.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Homeobox protein LH-2; LIM homeo box protein 2; LIM homeobox protein 2; LIM HOX gene 2; LIM/homeobox protein Lhx2; MGC138390
Gene Aliases: ap; apterous; hLhx2; Lh-2; LH2; LH2A; LHX2; Lim2
UniProt ID: (Human) P50458, (Mouse) Q9Z0S2
Entrez Gene ID: (Human) 9355, (Mouse) 16870, (Rat) 296706
transcription factor activity, RNA polymerase II transcription factor binding
chromatin binding
zinc ion binding
sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
DNA binding
protein binding
metal ion binding
helix-turn-helix transcription factor
homeodomain transcription factor
DNA-binding transcription factor
gene-specific transcriptional regulator
neural tube closure
hair follicle development
transcription, DNA-templated
axon guidance
mesoderm development
dorsal/ventral pattern formation
olfactory bulb development
telencephalon regionalization
cerebral cortex development
maintenance of epithelial cell apical/basal polarity
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
axon extension
retina development in camera-type eye
negative regulation of transcription regulatory region DNA binding
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
nervous system development
brain development
telencephalon development
neurogenesis
neuron differentiation
anatomical structure formation involved in morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support