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Invitrogen
LIFR Recombinant Rabbit Monoclonal Antibody (PSH08-76)
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FIGURE: 1 / 1
LIFR Antibody (MA570055) in WB
Western blot analysis of LIFR in various lysates. Samples were incubated with LIFR monoclonal antibody (Product # MA570055) using a dilution of 1:2,000 in 5% NFDM/TBST at 4°C overnight followed by Goat Anti-Rabbit IgG - HRP Secondary Antibody at a dilution of 1:50,000 for 1 hour at room temperature. Lane 1: HeLa cell lysate; Lane 2: PANC-1 cell lysate; Lane 3: T-47D cell lysate (negative); Lane 4: MDA-MB-231 cell lysate; Lane 5: HCT 116 cell lysate; Lane 6: RD cell lysate. Lysates/proteins at 20 µg/Lane. Predicted band size: 124 kDa; Obser... View More
Product Details
MA570055
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
PSH08-76
Immunogen
Recombinant protein within human LIFR aa 1-850.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Positive control: HeLa cell lysate, PANC-1 cell lysate, MDA-MB-231 cell lysate, HCT 116 cell lysate, RD cell lysate.
Subcellular location: Cell membrane.
Target Information
Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD118; CD118 antigen; FLJ98106; FLJ99923; Leukemia inhibitory factor receptor; LIF R beta; LIF receptor
Gene Aliases: CD118; LIF-R; LIFR; SJS2; STWS; SWS
UniProt ID: (Human) P42702
Entrez Gene ID: (Human) 3977
cell surface receptor signaling pathway
positive regulation of cell proliferation
negative regulation of muscle cell apoptotic process
response to organic cyclic compound
cytokine-mediated signaling pathway
organ regeneration
response to cytokine
oncostatin-M-mediated signaling pathway
neuron projection morphogenesis
leukemia inhibitory factor signaling pathway
ciliary neurotrophic factor-mediated signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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