This Antibody was verified by Knockout to ensure that the antibody binds to the antigen stated. View Details
It is not recommended to aliquot this antibody.
LKB1 (also known as STK11 - Serine/threonine-protein kinase STK11), a member of the serine/threonine kinase family, is a tumor suppressor. LKB1 physically associates with p53 and regulates specific p53 dependent apoptosis pathways. LKB1 is present in both the cytoplasm and nucleus of living cells and translocates to mitochondria during apoptosis. LKB1 functions as a master upstream protein kinase, regulating AMPK related kinases as well as AMPK. Mutations in LKB1 gene are associated with Peutz Jeghers syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CAMK group; CAMKL family; Liver kinase B1; LKB 1; LKB-1; LKB1; LKB1(S); polarization-related protein LKB1; Renal carcinoma antigen NY-REN-19; serine/threonine-protein kinase 11; serine/threonine-protein kinase LKB1; Serine/threonine-protein kinase STK11
Gene Aliases: hLKB1; LKB1; PJS; STK11
UniProt ID: (Human) Q15831
Entrez Gene ID: (Human) 6794
Molecular Function: non-receptor serine/threonine protein kinase