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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 15 amino acid peptide from 2nd cytoplasmic domain of human EDG7.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||4 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Mouse, Bovine, Dog, Bat, Elephant, Horse, Opossum (100%).
EDG7 is a member of the G protein-coupled receptor family, as well as the EDG family of proteins. This protein functions as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization. This receptor couples predominantly to G(q/11) alpha proteins.EDG7 has been reported in human prostate, as well as rodent brain, kidney, lung, placenta, prostate, and testis. ESTs have been isolated from a normal prostate library, as well as cancer libraries of the head/neck, ovary, and thyroid.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
calcium-mobilizing lysophosphatidic acid receptor LP-A3; Edg-7; EDG7; endothelial cell differentiation gene 7; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7; HOFNH30; LP-A3; LPA receptor 3; LPA receptor EDG7; LPA-3; LPA3; LPAR3; lysophosphatidic acid receptor Edg-7; RP4-678I3
Edg-7; EDG7; GPCR; HOFNH30; LP-A3; LPA3; LPAR3; RP4-678I3