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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 16 amino acid peptide from ligand-binding domain of human NR5A2.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||10 - 19 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Elephant, Panda, Horse, Pig (100%).
Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
b1-binding factor, hepatocyte transcription factor which activates enhancer II of hepatitis B virus; B1F; B1F2; CPF; CYP7A promoter-binding factor; fetoprotein-alpha 1 (AFP) transcription factor; FTF; FTZ-F1; FTZ-F1beta; HB1F; HB1F-2; hepatocytic transcription factor hB1F-3; liver nuclear receptor homolog-1 variant 2; Liver receptor homolog-1; LRH-1; LRH1; NR5A2; Nuclear receptor NR5A2; Nuclear receptor phr-1; nuclear receptor subfamily 5, group A, member 2; Receptor phr
B1F; B1F2; CPF; FTF; FTZ-F1; FTZ-F1beta; hB1F-2; LRH-1; LRH1; NR5A2