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Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:400 | - |
Immunohistochemistry (Frozen) (IHC (F)) |
1:200 | - |
Product Specifications | |
---|---|
Species Reactivity |
Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
(C)GRYDANLQ(S)ASPE, corresponding to amino acid residues 334-346 of mouse LRRTM1, Extracellular, N-terminus |
Conjugate |
Unconjugated |
Form |
Lyophilized |
Concentration |
0.8 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.4, with 1% BSA |
Contains |
0.05% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
Reconstitution: 1 X 50 µL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Each LRRTM protein is a type I transmembrane containing ten extracellular leucine-rich repeats and a short intracellular tail and has a developmentally regulated pattern distinct from all others. LRRTM1 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: leucine-rich repeat transmembrane neuronal 1; Leucine-rich repeat transmembrane neuronal protein 1
Gene Aliases: 4632401D06Rik; AW125451; Lrrtm1
UniProt ID: (Rat) D4A6D8, (Mouse) Q8K377
Entrez Gene ID: (Rat) 679668, (Mouse) 74342
Molecular Function:
transmembrane signal receptor
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