Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family. Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.
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Protein Aliases: cancer-associated Sm protein; Cancer-associated Sm-like; cancer-associated Sm-like protein; cancer‐associated Sm protein; LSM1 homolog, U6 small nuclear RNA associated; LSM1 mRNA degradation associated; LSM1, U6 small nuclear RNA associated; LSM1-like protein U6 small nuclear RNA associated; Small nuclear ribonuclear CaSm; U6 snRNA-associated Sm-like protein LSm1
Gene Aliases: CASM; LSM1; YJL124C
UniProt ID: (Human) O15116
Entrez Gene ID: (Human) 27257
Molecular Function: RNA splicing factor