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|Tested species reactivity||Human|
|Host / Isotype||Rat / IgG1|
|Immunogen||Fusion protein corresponding to the cysteine-rich region (residues 28-220) of human LTBR, fused to the Fc portion of human IgG1.|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-25845 detects LTBR from human samples.
MA1-25845 has been successfully used in immunoprecipitation procedures.
The MA1-25845 immunogen is a fusion protein corresponding to the cysteine-rich region (residues 28-220) of human LTBR, fused to the Fc portion of human IgG1.
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphtoxin-beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CD18; D12S370; LT-BETA-R; lymphotoxin B receptor; lymphotoxin beta receptor (TNFR superfamily, member 3); TNF-R-III; TNFCR; TNFR-RP; TNFR2-RP; TNFRSF3; tumor necrosis factor C receptor; tumor necrosis factor receptor 2-related protein; tumor necrosis factor receptor type III
CD18; D12S370; LT-BETA-R; LTBR; TNF-R-III; TNFCR; TNFR-RP; TNFR2-RP; TNFR3; TNFRSF3