|ELISA (ELISA)||Assay dependent|
|Western Blot (WB)||Assay dependent|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified, full length, native, human lactoferrin protein.|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
|Storage conditions||4° C, do not freeze|
MA1-20058 detects lactoferrin in human samples.
MA1-20058 has been successfully used in ELISA and Western blot procedures.
The MA1-20058 immunogen is purified, full length, native, human lactoferrin protein.
Lactoferrin is an iron binding glycoprotein with a molecular weight of ~80 kDa. The protein has two iron binding domains each housing one Fe3+ and the synergistic CO32- ion. The crystal structure form of human lactoferrin at 2.2A resolution exhibits 5330 protein atoms, 2Fe2+, 2CO32- and 98 carbohydrate atoms. Lactoferrin is absorbed from intestine by apical side of the membrane and localized to the nuclei. Intravenous infusion of lactoferrin is protective against lethal doses of E coli and induce bacterimia by a mechanism that downregulates neutrophil TNF alfa secretion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: epididymis luminal protein 110; Growth-inhibiting protein 12; kaliocin-1; lactoferricin; Lactoferrin; lactoferroxin; Lactotransferrin; neutrophil lactoferrin; Talalactoferrin
Gene Aliases: GIG12; HEL110; HLF2; LF; LTF
UniProt ID: (Human) Q96KZ5
Entrez Gene ID: (Human) 4057
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