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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 270 and 331 of Human Laforin|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 40% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:1000-1:10,000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-28073 targets Laforin in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-28073 immunogen is synthetic peptide corresponding to a region within amino acids 270 and 331 of Human Laforin.
This gene encodes a dual-specificity phosphatase that associates with polyribosomes. The encoded protein may be involved in the regulation of glycogen metabolism. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
epilepsy; epilepsy, progressive myoclonus type 2, Lafora disease (laforin); EPM2; EPM2A; glucan phosphatase; Lafora disease (laforin); lafora PTPase; laforin; LAFPTPase; MELF; progressive myoclonus type 2
EPM2; EPM2A; MELF