|Flow Cytometry (Flow)||1ug/ml|
|Immunohistochemistry (Paraffin) (IHC (P))||2-4ug/ml|
|Western Blot (WB)||1ug/ml|
|Immunohistochemistry (IHC)||See 2 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Not Applicable|
|Host / Isotype||Mouse / IgG1/IgG2a|
|Clone||LAM03 + HP6054|
|Immunogen||Purified human Lambda light chain, and purified human IgG myeloma proteins covalently coupled to polyaminostyrene micro beads|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
|Target||Lambda light chain|
By Western blot, MA5-11590 detects Human Ig lambda light chain at ~25kD in human samples.
By ELISA and WB, MA5-11590 does not react with human Ig kappa light chain.
Antibody to the lambda light chain of immunoglobulin is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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