|Tested species reactivity||Human|
|Published species reactivity||Not Applicable|
|Host / Isotype||Mouse / IgG1/IgG2a|
|Clone||LAM03 + HP6054|
|Immunogen||Purified human Lambda light chain, and purified human IgG myeloma proteins covalently coupled to polyaminostyrene micro beads|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Target||Lambda light chain|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1ug/ml|
|Immunohistochemistry (Paraffin) (IHC (P))||2-4ug/ml|
|Western Blot (WB)||1ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 2 publications below|
By Western blot, MA5-11590 detects Human Ig lambda light chain at ~25kD in human samples.
By ELISA and WB, MA5-11590 does not react with human Ig kappa light chain.
Antibody to the lambda light chain of immunoglobulin is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Composite lymphoma in the anterior mediastinum: a case report and review of the literature.
MA5-11590 was used in immunohistochemistry to present a case report of an unusual composite lymphoma in the mediastinum
|Yu G,Kong L,Qu G,Zhang Q,Wang W,Jiang L||Diagnostic pathology (6:null)||2011|
|Not Applicable||Not Cited||
Anetodermic primary cutaneous B-cell lymphoma: a unique clinicopathological presentation of lymphoma possibly associated with antiphospholipid antibodies.
MA5-11590 was used in immunohistochemistry to investigate clinical and histopathological features of anetodermic primary cutaneous B-cell lymphoma
|Hodak E,Feuerman H,Barzilai A,David M,Cerroni L,Feinmesser M||Archives of dermatology (146:175)||2010|