|ELISA (ELISA)||0.1-1.0 ug/ml|
|Flow Cytometry (Flow)||3-5 µg/10^6 cells|
|Immunofluorescence (IF)||5-10 ug/ml|
|Immunoprecipitation (IP)||2.5-5 ug|
|Western Blot (WB)||2 µg/ml|
|Western Blot (WB)||See 25 publications below|
|Miscellaneous PubMed (MISC)||See 5 publications below|
|Immunohistochemistry (IHC)||See 1 publications below|
|Immunoprecipitation (IP)||See 2 publications below|
|Immunohistochemistry (Paraffin) (IHC (P))||See 1 publications below|
|Tested Species reactivity||Chicken, Human, Mouse, Rat|
|Published species reactivity||Rat , Non-human primate , Mouse , Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Extracts from chicken nuclei|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. The gamma 1 chain, formerly thought to be a beta chain, contains structural domains similar to beta chains, however, lacks the short alpha region separating domains I and II. The structural organization of this gene also suggested that it had diverged considerably from the beta chain genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ADLD; Lamin-B1; LMN; LMN2; LMNB
Gene Aliases: ADLD; LMN; LMN2; LMNB; LMNB1
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