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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Purified native Laminin alpha-5.|
|Contains||0.09% sodium azide|
|Storage Conditions||4°C or -20°C if preferred|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Immunofluorescence (IF)||Assay Dependent|
|Immunoprecipitation (IP)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Gel Shift (GS)||See 1 publications below|
This antibody does not react with mouse or rat.
Components of the extracellular matrix exert myriad effects on tissues throughout the body. In particular, the laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in such diverse organs as the kidney, lung, skin, and nervous system. It is thought that laminins mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminins function as heterotrimeric complexes of alpha, beta, and gamma chains, with each chain type representing a different subfamily of proteins. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Two transcript variants encoding different isoforms have been found for this gene, but the full-length nature of one of them has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Identification of an estrogen response element activated by metabolites of 17beta-estradiol and raloxifene.
MA1-83286 was used in EMSA assay to investigate the mechanism for the regulation of gene expression by 17 beta-estradiol and raloxifene
|Yang NN,Venugopalan M,Hardikar S,Glasebrook A||Science (New York, N.Y.) (273:1222)||1996|
KIAA1907; laminin alpha-5 chain; laminin-10 subunit alpha; laminin-11 subunit alpha; laminin-15 subunit alpha; RP11-157P1.6
KIAA0533; KIAA1907; LAMA5