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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 364 and 620 of Human Lingo-1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-31282 targets Lingo-1 in WB applications and shows reactivity with Human samples.
The PA5-31282 immunogen is recombinant fragment corresponding to a region within amino acids 364 and 620 of Human Lingo-1.
Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
LERN1; leucine rich repeat neuronal 6A; leucine-rich repeat; leucine-rich repeat and immunoglobilin domain-containing protein 1; leucine-rich repeat and immunoglobulin domain-containing protein 1; leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; leucine-rich repeat neuronal protein 1; LRRN6A; UNQ201
LERN1; LINGO1; LRRN6A; UNQ201; UNQ201/PRO227