|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Purified human LH-beta|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:2000-4000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 5 publications below|
MA5-12138 targets Luteinizing Hormone in IHC (P) applications and shows reactivity with Human samples.
The MA5-12138 immunogen is purified human LH-beta.
Luteinizing hormone (LH) is a tropic hormone which modulates the secretory activity of other endocrine glands. It is produced in the anterior hypophysis of the pituitary gland. The glycoprotein hormone, LH, like follicle stimulating hormone and thyroid stimulating hormone, is composed of a common alpha-subunit but also a spesofic beta-subunit, which characterizes each of these hormones.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Activation and regulation of endogenous retroviral genes in the human pituitary gland and related endocrine tumours.
MA5-12138 was used in immunohistochemistry to study the potential involvement of endogenous retroviral genes in the development of pituitary adenomas
|Buslei R,Strissel PL,Henke C,Schey R,Lang N,Ruebner M,Stolt CC,Fabry B,Buchfelder M,Strick R||Neuropathology and applied neurobiology (41:180)||2015|
Clinicopathological investigation of vascular endothelial growth factor and von Hippel-Lindau gene-related protein expression in immunohistochemically negative pituitary adenoma--possible involvement in tumor aggressiveness.
MA5-12138 was used in immunohistochemistry to study the clinical significance of VEGF and pVHL expression in immunohistochemically negative pituitary adenomas
|Shimoda Y,Ogawa Y,Watanabe M,Tominaga T||Endocrine research (38:242)||2013|
Transsphenoidal microsurgical results of female patients with prolactinomas.
MA5-12138 was used in immunohistochemistry to study the efficacy and complications of trans-sphenoidal microsurgery in prolactinoma patients hoping to become pregnant
|Ikeda H,Watanabe K,Tominaga T,Yoshimoto T||Clinical neurology and neurosurgery (115:1621)||2013|
Incidence, hormonal distribution and postoperative follow up of atypical pituitary adenomas.
MA5-12138 was used in immunohistochemistry to report on the incidence and post-operative follow up of cases of atypical pituitary adenoma
|Yildirim AE,Divanlioglu D,Nacar OA,Dursun E,Sahinoglu M,Unal T,Belen AD||Turkish neurosurgery (23:226)||2013|
KIT protein expression and mutational status of KIT gene in pituitary adenomas.
MA5-12138 was used in immunohistochemistry to look for KIT gene mutations and study the immunohistochemical expression of KIT in pituitary adenomas
|Casar-Borota O,Fougner SL,Bollerslev J,Nesland JM||Virchows Archiv : an international journal of pathology (460:171)||2012|