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|Tested species reactivity||Mouse|
|Host / Isotype||Syrian hamster / IgG|
|Storage buffer||proprietary buffer|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
KLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA3 is thought to be an inhibitory receptor, recognizing peptide -receptive H-2Kb.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
cytomegalovirus resistance 1; killer cell lectin-like receptor 3; killer cell lectin-like receptor 6; killer cell lectin-like receptor 8; Klra3; Klra6; Ly-49c; Ly-49f; ly-49h; Ly49-f; Ly49C; Ly49F; lymphocyte antigen 49c; lymphocyte antigen 49f; lymphocyte antigen 49h; natural killer cell-associated antigen 2; T-cell surface glycoprotein Ly-49C; T-cell surface glycoprotein Ly-49F; T-cell surface glycoprotein Ly-49H
5E6; Cmv-1; Cmv1; Klra3; Klra6; Klra8; Ly-49c; Ly-49f; Ly-49h; Ly49-f; Ly49-h; Ly49C; Ly49F; Ly49H; Ly49u<129>; Nk-2; NK-2.1; Nk2; Nk2.1