Product References
XIAOPI formula inhibits the pre-metastatic niche formation in breast cancer via suppressing TAMs/CXCL1 signaling.
Cell communication and signaling : CCS
Zheng Y,Wang N,Wang S,Yang B,Situ H,Zhong L,Lin Y,Wang Z
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu Mar 26 00:00:00 EDT 2020
Multipotency of mouse trophoblast stem cells.
Stem cell research & therapy
Hou M,Han J,Li G,Kwon MY,Jiang J,Emani S,Taglauer ES,Park JA,Choi EB,Vodnala M,Fong YW,Emani SM,Rosas IO,Perrella MA,Liu X
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu Feb 13 00:00:00 EST 2020
PDGFRA defines the mesenchymal stem cell Kaposi's sarcoma progenitors by enabling KSHV oncogenesis in an angiogenic environment.
PLoS pathogens
Naipauer J,Rosario S,Gupta S,Premer C,Méndez-Solís O,Schlesinger M,Ponzinibbio V,Jain V,Gay L,Renne R,Chan HL,Morey L,Salyakina D,Abba M,Williams S,Hare JM,Goldschmidt-Clermont PJ,Mesri EA
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Sun Dec 01 00:00:00 EST 2019
The Inhibition of CD39 and CD73 Cell Surface Ectonucleotidases by Small Molecular Inhibitors Enhances the Mobilization of Bone Marrow Residing Stem Cells by Decreasing the Extracellular Level of Adenosine.
Stem cell reviews and reports
Adamiak M,Bujko K,Brzezniakiewicz-Janus K,Kucia M,Ratajczak J,Ratajczak MZ
15-5981 was used in Flow cytometry/Cell sorting to demonstrate mobilization of hematopoietic stem progenitor cells as well as other types of BM-residing stem cells is facilitated by CD39 and CD73 inhibitors.
Sun Dec 01 00:00:00 EST 2019
Procr-expressing progenitor cells are responsible for murine ovulatory rupture repair of ovarian surface epithelium.
Nature communications
Wang J,Wang D,Chu K,Li W,Zeng YA
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu Oct 31 00:00:00 EDT 2019
Macrophages fine tune satellite cell fate in dystrophic skeletal muscle of mdx mice.
PLoS genetics
Madaro L,Torcinaro A,De Bardi M,Contino FF,Pelizzola M,Diaferia GR,Imeneo G,Bouchè M,Puri PL,De Santa F
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia.
Cancer cell
Baccelli I,Gareau Y,Lehnertz B,Gingras S,Spinella JF,Corneau S,Mayotte N,Girard S,Frechette M,Blouin-Chagnon V,Leveillé K,Boivin I,MacRae T,Krosl J,Thiollier C,Lavallée VP,Kanshin E,Bertomeu T,Coulombe-Huntington J,St-Denis C,Bordeleau ME,Boucher G,Roux PP,Lemieux S,Tyers M,Thibault P,Hébert J,Marinier A,Sauvageau G
15-5981 was used in Flow cytometry/Cell sorting to identify an ETC complex I inhibitor and reveals the genetic landscape of OXPHOS dependency in AML.
Mon Jul 08 00:00:00 EDT 2019
Excessive exosome release is the pathogenic pathway linking a lysosomal deficiency to generalized fibrosis.
Science advances
van de Vlekkert D,Demmers J,Nguyen XX,Campos Y,Machado E,Annunziata I,Hu H,Gomero E,Qiu X,Bongiovanni A,Feghali-Bostwick CA,d'Azzo A
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Mon Jul 01 00:00:00 EDT 2019
The microRNAs miR-204 and miR-211 maintain joint homeostasis and protect against osteoarthritis progression.
Nature communications
Huang J,Zhao L,Fan Y,Liao L,Ma PX,Xiao G,Chen D
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Fri Jun 28 00:00:00 EDT 2019
TGFβ-induced degradation of TRAF3 in mesenchymal progenitor cells causes age-related osteoporosis.
Nature communications
Li J,Ayoub A,Xiu Y,Yin X,Sanders JO,Mesfin A,Xing L,Yao Z,Boyce BF
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Wed Jun 26 00:00:00 EDT 2019
Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy.
Nature communications
Welc SS,Flores I,Wehling-Henricks M,Ramos J,Wang Y,Bertoni C,Tidball JG
15-5981 was used in Flow cytometry/Cell sorting to study the effect of expression of a therapeutic transgene in leukocyte progenitors that invade muscle on selective and timely delivery to diseased muscle.
Wed Jun 26 00:00:00 EDT 2019
Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus.
eLife
Moretti FA,Klapproth S,Ruppert R,Margraf A,Weber J,Pick R,Scheiermann C,Sperandio M,Fässler R,Moser M
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu Sep 06 00:00:00 EDT 2018
Novel evidence that extracellular nucleotides and purinergic signaling induce innate immunity-mediated mobilization of hematopoietic stem/progenitor cells.
Leukemia
Adamiak M,Bujko K,Cymer M,Plonka M,Glaser T,Kucia M,Ratajczak J,Ulrich H,Abdel-Latif A,Ratajczak MZ
15-5981 was used in Flow cytometry/Cell sorting to demonstrate that ATP and its metabolite adenosine have an important role in the egress of hematopoietic stem progenitor cells from bone marrow niches into peripheral blood.
Sat Sep 01 00:00:00 EDT 2018
Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow.
Nature communications
Xu C,Gao X,Wei Q,Nakahara F,Zimmerman SE,Mar J,Frenette PS
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Fri Jun 22 00:00:00 EDT 2018
The H3K4 methyltransferase Setd1b is essential for hematopoietic stem and progenitor cell homeostasis in mice.
eLife
Schmidt K,Zhang Q,Tasdogan A,Petzold A,Dahl A,Arneth BM,Slany R,Fehling HJ,Kranz A,Stewart AF,Anastassiadis K
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Tue Jun 19 00:00:00 EDT 2018
Signaling of the Complement Cleavage Product Anaphylatoxin C5a Through C5aR (CD88) Contributes to Pharmacological Hematopoietic Stem Cell Mobilization.
Stem cell reviews and reports
Bujko K,Rzeszotek S,Hoehlig K,Yan J,Vater A,Ratajczak MZ
15-5981 was used in Flow cytometry/Cell sorting to show mice deficient in C5aR, and thus unable to mediate signaling of the complement cleavage product anaphylatoxin C5, have poor mobilization of hematopoietic stem/progenitor cells.
Fri Dec 01 00:00:00 EST 2017
Microgrooved-surface topography enhances cellular division and proliferation of mouse bone marrow-derived mesenchymal stem cells.
PloS one
Chaudhary JK,Rath PC
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu Oct 19 00:00:00 EDT 2017
Zoledronate suppressed angiogenesis and osteogenesis by inhibiting osteoclasts formation and secretion of PDGF-BB.
PloS one
Gao SY,Zheng GS,Wang L,Liang YJ,Zhang SE,Lao XM,Li K,Liao GQ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Mon Sep 18 00:00:00 EDT 2017
FOXP1 controls mesenchymal stem cell commitment and senescence during skeletal aging.
The Journal of clinical investigation
Li H,Liu P,Xu S,Li Y,Dekker JD,Li B,Fan Y,Zhang Z,Hong Y,Yang G,Tang T,Ren Y,Tucker HO,Yao Z,Guo X
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Mon Apr 03 00:00:00 EDT 2017
GATA4-dependent organ-specific endothelial differentiation controls liver development and embryonic hematopoiesis.
The Journal of clinical investigation
Géraud C,Koch PS,Zierow J,Klapproth K,Busch K,Olsavszky V,Leibing T,Demory A,Ulbrich F,Diett M,Singh S,Sticht C,Breitkopf-Heinlein K,Richter K,Karppinen SM,Pihlajaniemi T,Arnold B,Rodewald HR,Augustin HG,Schledzewski K,Goerdt S
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Induced p53 loss in mouse luminal cells causes clonal expansion and development of mammary tumours.
Nature communications
Tao L,Xiang D,Xie Y,Bronson RT,Li Z
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Mon Feb 13 00:00:00 EST 2017
Inducible Nitric Oxide Synthase (iNOS) Is a Novel Negative Regulator of Hematopoietic Stem/Progenitor Cell Trafficking.
Stem cell reviews and reports
Adamiak M,Abdelbaset-Ismail A,Moore JB,Zhao J,Abdel-Latif A,Wysoczynski M,Ratajczak MZ
15-5981 was used in Flow cytometry/Cell sorting to indicate that inducible nitric oxide synthetase is a negative regulator of hematopoietic cell migration.
Wed Feb 01 00:00:00 EST 2017
Mutant U2AF1-expressing cells are sensitive to pharmacological modulation of the spliceosome.
Nature communications
Shirai CL,White BS,Tripathi M,Tapia R,Ley JN,Ndonwi M,Kim S,Shao J,Carver A,Saez B,Fulton RS,Fronick C,O'Laughlin M,Lagisetti C,Webb TR,Graubert TA,Walter MJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Mon Jan 09 00:00:00 EST 2017
Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease.
Nature medicine
Hahm E,Wei C,Fernandez I,Li J,Tardi NJ,Tracy M,Wadhwani S,Cao Y,Peev V,Zloza A,Lusciks J,Hayek SS,O'Connor C,Bitzer M,Gupta V,Sever S,Sykes DB,Scadden DT,Reiser J
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2017
Identification of an epidermal keratinocyte AMPA glutamate receptor involved in dermatopathies associated with sensory abnormalities.
Pain reports
Cabañero D,Irie T,Celorrio M,Trousdale C,Owens DM,Virley D,Albrecht PJ,Caterina MJ,Rice FL,Morón JA
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.
Cell
Damgaard RB,Walker JA,Marco-Casanova P,Morgan NV,Titheradge HL,Elliott PR,McHale D,Maher ER,McKenzie ANJ,Komander D
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu Aug 25 00:00:00 EDT 2016
Evidence that a lipolytic enzyme--hematopoietic-specific phospholipase C-β2--promotes mobilization of hematopoietic stem cells by decreasing their lipid raft-mediated bone marrow retention and increasing the promobilizing effects of granulocytes.
Leukemia
Adamiak M,Poniewierska-Baran A,Borkowska S,Schneider G,Abdelbaset-Ismail A,Suszynska M,Abdel-Latif A,Kucia M,Ratajczak J,Ratajczak MZ
15-5981 was used in Flow cytometry/Cell sorting to report the role of hematopoietic cell-specific phospholipase C-β2 (PLC-β2) in the pharmacological mobilization of hematopoietic stem/progenitor cells (HSPCs).
Fri Apr 01 00:00:00 EDT 2016
Hedgehog-driven myogenic tumors recapitulate skeletal muscle cellular heterogeneity.
Experimental cell research
Hettmer S,Lin MM,Tchessalova D,Tortorici SJ,Castiglioni A,Desai T,Mao J,McMahon AP,Wagers AJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
CD93 Marks a Non-Quiescent Human Leukemia Stem Cell Population and Is Required for Development of MLL-Rearranged Acute Myeloid Leukemia.
Cell stem cell
Iwasaki M,Liedtke M,Gentles AJ,Cleary ML
15-5981 was used in Flow cytometry/Cell sorting to study how CD93 expression may indicate leukaemia initiating stem cells that have a MLL gene rearrangement.
Thu Oct 01 00:00:00 EDT 2015
Cis-regulatory mechanisms governing stem and progenitor cell transitions.
Science advances
Johnson KD,Kong G,Gao X,Chang YI,Hewitt KJ,Sanalkumar R,Prathibha R,Ranheim EA,Dewey CN,Zhang J,Bresnick EH
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Paracrine Met signaling triggers epithelial-mesenchymal transition in mammary luminal progenitors, affecting their fate.
eLife
Di-Cicco A,Petit V,Chiche A,Bresson L,Romagnoli M,Orian-Rousseau V,Vivanco Md,Medina D,Faraldo MM,Glukhova MA,Deugnier MA
15-5981 was used in Flow cytometry/Cell sorting to indicate that paracrine Met signaling can control the function of luminal progenitors and modulate their fate during mammary development and tumorigenesis.
Mon Jul 13 00:00:00 EDT 2015
Mouse bone marrow-derived mesenchymal stem cells inhibit leukemia/lymphoma cell proliferation in vitro and in a mouse model of allogeneic bone marrow transplant.
International journal of molecular medicine
Song N,Gao L,Qiu H,Huang C,Cheng H,Zhou H,Lv S,Chen L,Wang J
15-5981 was used in Flow cytometry/Cell sorting to determine that MSCs may be safe and effective when used in allogeneic BMT for the treatment of haemotological malignancies.
Wed Jul 01 00:00:00 EDT 2015
Cellular and molecular characterization of human cardiac stem cells reveals key features essential for their function and safety.
Stem cells and development
Vahdat S,Mousavi SA,Omrani G,Gholampour M,Sotoodehnejadnematalahi F,Ghazizadeh Z,Gharechahi J,Baharvand H,Salekdeh GH,Aghdami N
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Mon Jun 15 00:00:00 EDT 2015
KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis.
Nature medicine
Shankman LS,Gomez D,Cherepanova OA,Salmon M,Alencar GF,Haskins RM,Swiatlowska P,Newman AA,Greene ES,Straub AC,Isakson B,Randolph GJ,Owens GK
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2015
Amniotic fluid stem cells prevent follicle atresia and rescue fertility of mice with premature ovarian failure induced by chemotherapy.
PloS one
Xiao GY,Liu IH,Cheng CC,Chang CC,Lee YH,Cheng WT,Wu SC
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu May 28 00:00:00 EDT 2015
Multi-Drug Resistance ABC Transporter Inhibition Enhances Murine Ventral Prostate Stem/Progenitor Cell Differentiation.
Stem cells and development
Samant MD,Jackson CM,Felix CL,Jones AJ,Goodrich DW,Foster BA,Huss WJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Fri May 15 00:00:00 EDT 2015
Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity.
Nature cell biology
Jeffery E,Church CD,Holtrup B,Colman L,Rodeheffer MS
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
Limited miR-17-92 overexpression drives hematologic malignancies.
Leukemia research
Danielson LS,Reavie L,Coussens M,Davalos V,Castillo-Martin M,Guijarro MV,Coffre M,Cordon-Cardo C,Aifantis I,Ibrahim S,Liu C,Koralov SB,Hernando E
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2015
Recruitment of bone marrow-derived cells to periodontal tissue defects.
Frontiers in cell and developmental biology
Kimura Y,Komaki M,Iwasaki K,Sata M,Izumi Y,Morita I
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Mon Nov 03 00:00:00 EST 2014
Evidence for Transfer of Membranes from Mesenchymal Stem Cells to HL-1 Cardiac Cells.
Stem cells international
Boomsma RA,Geenen DL
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Wed Oct 08 00:00:00 EDT 2014
WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner.
The Journal of experimental medicine
Xia P,Wang S,Huang G,Zhu P,Li M,Ye B,Du Y,Fan Z
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Mon Sep 22 00:00:00 EDT 2014
Cardiogenic genes expressed in cardiac fibroblasts contribute to heart development and repair.
Circulation research
Furtado MB,Costa MW,Pranoto EA,Salimova E,Pinto AR,Lam NT,Park A,Snider P,Chandran A,Harvey RP,Boyd R,Conway SJ,Pearson J,Kaye DM,Rosenthal NA
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Fri Apr 25 00:00:00 EDT 2014
Cell-autonomous heparanase modulates self-renewal and migration in bone marrow-derived mesenchymal stem cells.
Journal of biomedical science
Cheng CC,Lee YH,Lin SP,Huangfu WC,Liu IH
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu Mar 13 00:00:00 EDT 2014
Validation of the effects of TGF-β1 on tumor recurrence and prognosis through tumor retrieval and cell mechanical properties.
Cancer cell international
Wu TH,Chou YW,Chiu PH,Tang MJ,Hu CW,Yeh ML
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Mon Mar 03 00:00:00 EST 2014
Overexpressing sonic hedgehog peptide restores periosteal bone formation in a murine bone allograft transplantation model.
Molecular therapy : the journal of the American Society of Gene Therapy
Huang C,Tang M,Yehling E,Zhang X
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Sat Feb 01 00:00:00 EST 2014
A non-redundant function of cyclin E1 in hematopoietic stem cells.
Cell cycle (Georgetown, Tex.)
Campaner S,Viale A,De Fazio S,Doni M,De Franco F,D'Artista L,Sardella D,Pelicci PG,Amati B
15-5981 was used in Flow cytometry/Cell sorting to support a role for cyclin E1 in controlling the exit from quiescence in hematopoietic stem cells.
Sun Dec 01 00:00:00 EST 2013
Enhancing T lineage production in aged mice: a novel function of Foxn1 in the bone marrow niche.
Journal of immunology (Baltimore, Md. : 1950)
Zook EC,Zhang S,Gerstein RM,Witte PL,Le PT
15-5981 was used in Flow cytometry/Cell sorting to report that Foxn1 is expressed in wild-type BM and overexpressed in Foxn1Tg.
Sun Dec 01 00:00:00 EST 2013
A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL).
Disease models & mechanisms
Carofino BL,Ayanga B,Justice MJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Fri Nov 01 00:00:00 EDT 2013
HIF prolyl hydroxylase 2 (PHD2) is a critical regulator of hematopoietic stem cell maintenance during steady-state and stress.
Blood
Singh RP,Franke K,Kalucka J,Mamlouk S,Muschter A,Gembarska A,Grinenko T,Willam C,Naumann R,Anastassiadis K,Stewart AF,Bornstein S,Chavakis T,Breier G,Waskow C,Wielockx B
15-5981 was used in Flow cytometry/Cell sorting to study the role of PHD2 in HSC compartment maintenance.
Thu Jun 27 00:00:00 EDT 2013
Cis-element mutated in GATA2-dependent immunodeficiency governs hematopoiesis and vascular integrity.
The Journal of clinical investigation
Johnson KD,Hsu AP,Ryu MJ,Wang J,Gao X,Boyer ME,Liu Y,Lee Y,Calvo KR,Keles S,Zhang J,Holland SM,Bresnick EH
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2012
Induction of cardiac myogenic lineage development differs between mesenchymal and satellite cells and is accelerated by bone morphogenetic protein-4.
Journal of molecular and cellular cardiology
Grajales L,García J,Geenen DL
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2012
Thymus-autonomous T cell development in the absence of progenitor import.
The Journal of experimental medicine
Martins VC,Ruggiero E,Schlenner SM,Madan V,Schmidt M,Fink PJ,von Kalle C,Rodewald HR
15-5981 was used in Flow cytometry/Cell sorting to characterise the previously unrecognised capacity of the thymus to sustain T cell development during bone marrow progenitor deprivation.
Mon Jul 30 00:00:00 EDT 2012
CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion.
The EMBO journal
Gu P,Min JN,Wang Y,Huang C,Peng T,Chai W,Chang S
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Wed May 16 00:00:00 EDT 2012
Lunatic fringe deficiency cooperates with the Met/Caveolin gene amplicon to induce basal-like breast cancer.
Cancer cell
Xu K,Usary J,Kousis PC,Prat A,Wang DY,Adams JR,Wang W,Loch AJ,Deng T,Zhao W,Cardiff RD,Yoon K,Gaiano N,Ling V,Beyene J,Zacksenhaus E,Gridley T,Leong WL,Guidos CJ,Perou CM,Egan SE
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Tue May 15 00:00:00 EDT 2012
Essential roles for Pot1b in HSC self-renewal and survival.
Blood
Wang Y,Shen MF,Chang S
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2011
CD24-positive cells from normal adult mouse liver are hepatocyte progenitor cells.
Stem cells and development
Qiu Q,Hernandez JC,Dean AM,Rao PH,Darlington GJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2011
The earliest intrathymic precursors of CD8α(+) thymic dendritic cells correspond to myeloid-type double-negative 1c cells.
European journal of immunology
Luche H,Ardouin L,Teo P,See P,Henri S,Merad M,Ginhoux F,Malissen B
15-5981 was used in Flow cytometry/Cell sorting to provide evidence that myeloid-restricted progenitors generate the whole constellation of DCs present in the body, including the thymus.
Mon Aug 01 00:00:00 EDT 2011
A high omega-3 fatty acid diet has different effects on early and late stage myeloid progenitors.
Lipids
Varney ME,Buchanan JT,Dementieva Y,Hardman WE,Sollars VE
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Sat Jan 01 00:00:00 EST 2011
Additive and global functions of HoxA cluster genes in mesoderm derivatives.
Developmental biology
Di-Poï N,Koch U,Radtke F,Duboule D
15-5981 was used in Flow cytometry/Cell sorting to report that mutant mice lacking the entire HoxA cluster in mesodermal lineages display the expected spectrum of postnatal respiratory, cardiac and urogenital defects, previously reported for single gene mutations.
Sat May 15 00:00:00 EDT 2010
Delayed enrichment of mesenchymal cells promotes cardiac lineage and calcium transient development.
Journal of molecular and cellular cardiology
Grajales L,García J,Banach K,Geenen DL
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2010
Impaired mobilization of hematopoietic stem/progenitor cells in C5-deficient mice supports the pivotal involvement of innate immunity in this process and reveals novel promobilization effects of granulocytes.
Leukemia
Lee HM,Wu W,Wysoczynski M,Liu R,Zuba-Surma EK,Kucia M,Ratajczak J,Ratajczak MZ
15-5981 was used in Flow cytometry/Cell sorting to examine the central role of innate immunity in the mobilisation of haematopoietic stem/progenitor cells.
Sun Nov 01 00:00:00 EDT 2009
c-Myb is required for pro-B cell differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Fahl SP,Crittenden RB,Allman D,Bender TP
15-5981 was used in Flow cytometry/Cell sorting to demonstrate that c-Myb is absolutely required for the survival and differentiation of CD19(+) B-lineage cells.
Sun Nov 01 00:00:00 EDT 2009
A possible contribution of retinoids to regulation of fetal B lymphopoiesis.
European journal of immunology
Chen X,Welner RS,Kincade PW
15-5981 was used in Flow cytometry/Cell sorting to determine that retinoids may partially account for rapid differentiation in foetal life, but not for all unique features of foetal progenitors.
Tue Sep 01 00:00:00 EDT 2009
Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells.
Cell stem cell
Le Grand F,Jones AE,Seale V,Scimè A,Rudnicki MA
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Fri Jun 05 00:00:00 EDT 2009
A differentiation pathway for B1 cells in adult bone marrow.
Proceedings of the National Academy of Sciences of the United States of America
Esplin BL,Welner RS,Zhang Q,Borghesi LA,Kincade PW
15-5981 was used in Flow cytometry/Cell sorting to investigate the developmental origins of the B1-specified progenitor population in adult bone marrow.
Tue Apr 07 00:00:00 EDT 2009
Reporter gene-expressing bone marrow-derived stromal cells are immune-tolerated following implantation in the central nervous system of syngeneic immunocompetent mice.
BMC biotechnology
Bergwerf I,De Vocht N,Tambuyzer B,Verschueren J,Reekmans K,Daans J,Ibrahimi A,Van Tendeloo V,Chatterjee S,Goossens H,Jorens PG,Baekelandt V,Ysebaert D,Van Marck E,Berneman ZN,Linden AV,Ponsaerts P
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Wed Jan 07 00:00:00 EST 2009
Polysialic acid, a glycan with highly restricted expression, is found on human and murine leukocytes and modulates immune responses.
Journal of immunology (Baltimore, Md. : 1950)
Drake PM,Nathan JK,Stock CM,Chang PV,Muench MO,Nakata D,Reader JR,Gip P,Golden KP,Weinhold B,Gerardy-Schahn R,Troy FA,Bertozzi CR
15-5981 was used in Flow cytometry/Cell sorting to investigate the expression and possible function of polysialic acid in the immune system.
Sat Nov 15 00:00:00 EST 2008
Polysialic acid, a glycan with highly restricted expression, is found on human and murine leukocytes and modulates immune responses.
Journal of immunology (Baltimore, Md. : 1950)
Drake PM,Nathan JK,Stock CM,Chang PV,Muench MO,Nakata D,Reader JR,Gip P,Golden KP,Weinhold B,Gerardy-Schahn R,Troy FA,Bertozzi CR
15-5981 was used in Flow cytometry/Cell sorting to investigate the expression and possible function of polysialic acid in the immune system.
Sat Nov 15 00:00:00 EST 2008
E47 controls the developmental integrity and cell cycle quiescence of multipotential hematopoietic progenitors.
Journal of immunology (Baltimore, Md. : 1950)
Yang Q,Kardava L,St Leger A,Martincic K,Varnum-Finney B,Bernstein ID,Milcarek C,Borghesi L
15-5981 was used in Flow cytometry/Cell sorting to show E47 controls the developmental integrity and cell cycle quiescence of hematopoietic progenitors.
Sat Nov 01 00:00:00 EDT 2008
Lymphoid precursors are directed to produce dendritic cells as a result of TLR9 ligation during herpes infection.
Blood
Welner RS,Pelayo R,Nagai Y,Garrett KP,Wuest TR,Carr DJ,Borghesi LA,Farrar MA,Kincade PW
15-5981 was used in Flow cytometry/Cell sorting to show that common lymphoid progenitors from mice with active HSV-1 infection are biased to dendritic cell differentiation.
Sat Nov 01 00:00:00 EDT 2008
Contrasting responses of lymphoid progenitors to canonical and noncanonical Wnt signals.
Journal of immunology (Baltimore, Md. : 1950)
Malhotra S,Baba Y,Garrett KP,Staal FJ,Gerstein R,Kincade PW
15-5981 was used in Flow cytometry/Cell sorting to learn whether, and how, particular stages of B lymphopoiesis are responsive to Wnt family ligands.
Mon Sep 15 00:00:00 EDT 2008
MN1 overexpression induces acute myeloid leukemia in mice and predicts ATRA resistance in patients with AML.
Blood
Heuser M,Argiropoulos B,Kuchenbauer F,Yung E,Piper J,Fung S,Schlenk RF,Dohner K,Hinrichsen T,Rudolph C,Schambach A,Baum C,Schlegelberger B,Dohner H,Ganser A,Humphries RK
15-5981 was used in Flow cytometry/Cell sorting to study the effect of MN1 overexpression in mice and human patients with acute myeloid leukemia and predict ATRA resistance.
Sat Sep 01 00:00:00 EDT 2007
The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages.
Genes & development
Iwasaki H,Mizuno S,Arinobu Y,Ozawa H,Mori Y,Shigematsu H,Takatsu K,Tenen DG,Akashi K
15-5981 was used in Flow cytometry/Cell sorting to show that the expression timing of GATA-2 and CCAAT enhancer-binding protein alpha can differentially control their lineage commitment.
Wed Nov 01 00:00:00 EST 2006
Primitive lymphoid progenitors in bone marrow with T lineage reconstituting potential.
Journal of immunology (Baltimore, Md. : 1950)
Perry SS,Welner RS,Kouro T,Kincade PW,Sun XH
15-5981 was used in Flow cytometry/Cell sorting to determine which T cell subset colonise the thymus under normal circumstances, by side by side comparison of the three categories of bone marrow cells with T lymphopoietic potential.
Fri Sep 01 00:00:00 EDT 2006
Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment.
Immunity
Nagai Y,Garrett KP,Ohta S,Bahrun U,Kouro T,Akira S,Takatsu K,Kincade PW
15-5981 was used in Flow cytometry/Cell sorting to investigate the expression of toll-like receptors on different hematopoietic stem cells and the mechanism by which they stimulate innate immune system replenishment.
Thu Jun 01 00:00:00 EDT 2006
Identification of eosinophil lineage-committed progenitors in the murine bone marrow.
The Journal of experimental medicine
Iwasaki H,Mizuno S,Mayfield R,Shigematsu H,Arinobu Y,Seed B,Gurish MF,Takatsu K,Akashi K
15-5981 was used in Flow cytometry/Cell sorting to show that newly identified eosinophil lineage-committed progenitors could be the cellular target in the treatment of a variety of disorders mediated by eosinophils.
Mon Jun 20 00:00:00 EDT 2005
Hmgb3 deficiency deregulates proliferation and differentiation of common lymphoid and myeloid progenitors.
Blood
Nemeth MJ,Cline AP,Anderson SM,Garrett-Beal LJ,Bodine DM
15-5981 was used in Flow cytometry/Cell sorting to examine the role of Hmgb3 in adult haematopoiesis.
Sat Jan 15 00:00:00 EST 2005
Beta-catenin is dispensable for hematopoiesis and lymphopoiesis.
The Journal of experimental medicine
Cobas M,Wilson A,Ernst B,Mancini SJ,MacDonald HR,Kemler R,Radtke F
15-5981 was used in Flow cytometry/Cell sorting to investigate an essential role for beta-catenin during hematopoiesis and lymphopoiesis.
Mon Jan 19 00:00:00 EST 2004