Product References
The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut.
Biology open
Ramadan R,Wouters VM,van Neerven SM,de Groot NE,Garcia TM,Muncan V,Franklin OD,Battle M,Carlson KS,Leach J,Sansom OJ,Boulard O,Chamaillard M,Vermeulen L,Medema JP,Huels DJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu Dec 15 00:00:00 EST 2022
Cardiac Mesenchymal Stem Cells Promote Fibrosis and Remodeling in Heart Failure: Role of PDGF Signaling.
JACC. Basic to translational science
Hamid T,Xu Y,Ismahil MA,Rokosh G,Jinno M,Zhou G,Wang Q,Prabhu SD
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Sun May 01 00:00:00 EDT 2022
Hematopoietic-Mesenchymal Signals Regulate the Properties of Mesenchymal Stem Cells.
International journal of molecular sciences
Kanazawa S,Okada H,Riu D,Mabuchi Y,Akazawa C,Iwata J,Hoshi K,Hikita A
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Tue Jul 26 00:00:00 EDT 2022
Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia.
Cell stem cell
Vasquez EG,Nasreddin N,Valbuena GN,Mulholland EJ,Belnoue-Davis HL,Eggington HR,Schenck RO,Wouters VM,Wirapati P,Gilroy K,Lannagan TRM,Flanagan DJ,Najumudeen AK,Omwenga S,McCorry AMB,Easton A,Koelzer VH,East JE,Morton D,Trusolino L,Maughan T,Campbell AD,Loughrey MB,Dunne PD,Tsantoulis P,Huels DJ,Tejpar S,Sansom OJ,Leedham SJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu Aug 04 00:00:00 EDT 2022
Nociceptive nerves regulate haematopoietic stem cell mobilization.
Nature
Gao X,Zhang D,Xu C,Li H,Caron KM,Frenette PS
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Danger-associated molecular pattern molecules take unexpectedly a central stage in Nlrp3 inflammasome-caspase-1-mediated trafficking of hematopoietic stem/progenitor cells.
Leukemia
Thapa A,Adamiak M,Bujko K,Ratajczak J,Abdel-Latif AK,Kucia M,Ratajczak MZ
15-5981-82 was used in Flow Cytometry to investigate the role of the Nlrp3 inflammasome-caspase-1 axis in the release of danger-associated molecular pattern molecules for the mobilization of hematopoietic stem/progenitor cells.
Wed Sep 01 00:00:00 EDT 2021
Photoreceptor protection by mesenchymal stem cell transplantation identifies exosomal MiR-21 as a therapeutic for retinal degeneration.
Cell death and differentiation
Deng CL,Hu CB,Ling ST,Zhao N,Bao LH,Zhou F,Xiong YC,Chen T,Sui BD,Yu XR,Hu CH
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Mon Mar 01 00:00:00 EST 2021
Loss of p53 in mesenchymal stem cells promotes alteration of bone remodeling through negative regulation of osteoprotegerin.
Cell death and differentiation
Velletri T,Huang Y,Wang Y,Li Q,Hu M,Xie N,Yang Q,Chen X,Chen Q,Shou P,Gan Y,Candi E,Annicchiarico-Petruzzelli M,Agostini M,Yang H,Melino G,Shi Y,Wang Y
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
RANKL from bone marrow adipose lineage cells promotes osteoclast formation and bone loss.
EMBO reports
Hu Y,Li X,Zhi X,Cong W,Huang B,Chen H,Wang Y,Li Y,Wang L,Fang C,Guo J,Liu Y,Cui J,Cao L,Weng W,Zhou Q,Wang S,Chen X,Su J
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Mon Jul 05 00:00:00 EDT 2021
Effects of signaling pathway inhibitors on hematopoietic stem cells.
Molecular medicine reports
Jiang Y,Xu Z,Ma N,Yin L,Hao C,Li J
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
Age-related trabecular bone loss is associated with a decline in serum Galectin-1 level.
BMC musculoskeletal disorders
Xu W,Ni C,Wang Y,Zheng G,Zhang J,Xu Y
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Tue Apr 27 00:00:00 EDT 2021
Activation of skeletal muscle-resident glial cells upon nerve injury.
JCI insight
Proietti D,Giordani L,De Bardi M,D'Ercole C,Lozanoska-Ochser B,Amadio S,Volonté C,Marinelli S,Muchir A,Bouché M,Borsellino G,Sacco A,Puri PL,Madaro L
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu Apr 08 00:00:00 EDT 2021
Therapeutic Potential of Mesenchymal Stem Cells in a Pre-Clinical Model of Diabetic Kidney Disease and Obesity.
International journal of molecular sciences
Sávio-Silva C,Soinski-Sousa PE,Simplício-Filho A,Bastos RMC,Beyerstedt S,Rangel ÉB
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu Feb 04 00:00:00 EST 2021
MAEA is an E3 ubiquitin ligase promoting autophagy and maintenance of haematopoietic stem cells.
Nature communications
Wei Q,Pinho S,Dong S,Pierce H,Li H,Nakahara F,Xu J,Xu C,Boulais PE,Zhang D,Maryanovich M,Cuervo AM,Frenette PS
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Tue May 04 00:00:00 EDT 2021
The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism.
eLife
Roy A,Tomaz da Silva M,Bhat R,Bohnert KR,Iwawaki T,Kumar A
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Tue Nov 23 00:00:00 EST 2021
Troy/Tnfrsf19 marks epidermal cells that govern interfollicular epidermal renewal and cornification.
Stem cell reports
Kretzschmar K,Boonekamp KE,Bleijs M,Asra P,Koomen M,Chuva de Sousa Lopes SM,Giovannone B,Clevers H
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Tue Sep 14 00:00:00 EDT 2021
Conditionally pathogenic genetic variants of a hematopoietic disease-suppressing enhancer.
Science advances
Soukup AA,Matson DR,Liu P,Johnson KD,Bresnick EH
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Fri Dec 10 00:00:00 EST 2021
Multipotency of mouse trophoblast stem cells.
Stem cell research & therapy
Hou M,Han J,Li G,Kwon MY,Jiang J,Emani S,Taglauer ES,Park JA,Choi EB,Vodnala M,Fong YW,Emani SM,Rosas IO,Perrella MA,Liu X
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu Feb 13 00:00:00 EST 2020
Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase.
Nature communications
Wilkes MC,Siva K,Chen J,Varetti G,Youn MY,Chae H,Ek F,Olsson R,Lundbäck T,Dever DP,Nishimura T,Narla A,Glader B,Nakauchi H,Porteus MH,Repellin CE,Gazda HT,Lin S,Serrano M,Flygare J,Sakamoto KM
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Fri Jul 03 00:00:00 EDT 2020
XIAOPI formula inhibits the pre-metastatic niche formation in breast cancer via suppressing TAMs/CXCL1 signaling.
Cell communication and signaling : CCS
Zheng Y,Wang N,Wang S,Yang B,Situ H,Zhong L,Lin Y,Wang Z
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu Mar 26 00:00:00 EDT 2020
Use of Busulfan to Condition Mice for Bone Marrow Transplantation.
STAR protocols
Montecino-Rodriguez E,Dorshkind K
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Fri Dec 18 00:00:00 EST 2020
Phosphatase SHP1 impedes mesenchymal stromal cell immunosuppressive capacity modulated by JAK1/STAT3 and P38 signals.
Cell & bioscience
Jiang M,Ye J,Wang X,Li N,Wang Y,Shi Y
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu Apr 14 00:00:00 EDT 2022
Interaction of Deubiquitinase 2A-DUB/MYSM1 with DNA Repair and Replication Factors.
International journal of molecular sciences
Kroeger C,Roesler R,Wiese S,Hainzl A,Gatzka MV
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Tue May 26 00:00:00 EDT 2020
A novel function of R-spondin1 in regulating estrogen receptor expression independent of Wnt/β-catenin signaling.
eLife
Geng A,Wu T,Cai C,Song W,Wang J,Yu QC,Zeng YA
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Tue Aug 04 00:00:00 EDT 2020
Apoptotic bodies derived from mesenchymal stem cells promote cutaneous wound healing via regulating the functions of macrophages.
Stem cell research & therapy
Liu J,Qiu X,Lv Y,Zheng C,Dong Y,Dou G,Zhu B,Liu A,Wang W,Zhou J,Liu S,Liu S,Gao B,Jin Y
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Fri Nov 27 00:00:00 EST 2020
Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia.
Cancer cell
Baccelli I,Gareau Y,Lehnertz B,Gingras S,Spinella JF,Corneau S,Mayotte N,Girard S,Frechette M,Blouin-Chagnon V,Leveillé K,Boivin I,MacRae T,Krosl J,Thiollier C,Lavallée VP,Kanshin E,Bertomeu T,Coulombe-Huntington J,St-Denis C,Bordeleau ME,Boucher G,Roux PP,Lemieux S,Tyers M,Thibault P,Hébert J,Marinier A,Sauvageau G
15-5981 was used in Flow cytometry/Cell sorting to identify an ETC complex I inhibitor and reveals the genetic landscape of OXPHOS dependency in AML.
Mon Jul 08 00:00:00 EDT 2019
Long-term expansion and differentiation of adult murine epidermal stem cells in 3D organoid cultures.
Proceedings of the National Academy of Sciences of the United States of America
Boonekamp KE,Kretzschmar K,Wiener DJ,Asra P,Derakhshan S,Puschhof J,López-Iglesias C,Peters PJ,Basak O,Clevers H
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Tue Jul 16 00:00:00 EDT 2019
PDGFRA defines the mesenchymal stem cell Kaposi's sarcoma progenitors by enabling KSHV oncogenesis in an angiogenic environment.
PLoS pathogens
Naipauer J,Rosario S,Gupta S,Premer C,Méndez-Solís O,Schlesinger M,Ponzinibbio V,Jain V,Gay L,Renne R,Chan HL,Morey L,Salyakina D,Abba M,Williams S,Hare JM,Goldschmidt-Clermont PJ,Mesri EA
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Sun Dec 01 00:00:00 EST 2019
The Inhibition of CD39 and CD73 Cell Surface Ectonucleotidases by Small Molecular Inhibitors Enhances the Mobilization of Bone Marrow Residing Stem Cells by Decreasing the Extracellular Level of Adenosine.
Stem cell reviews and reports
Adamiak M,Bujko K,Brzezniakiewicz-Janus K,Kucia M,Ratajczak J,Ratajczak MZ
15-5981 was used in Flow cytometry/Cell sorting to demonstrate mobilization of hematopoietic stem progenitor cells as well as other types of BM-residing stem cells is facilitated by CD39 and CD73 inhibitors.
Sun Dec 01 00:00:00 EST 2019
Macrophages fine tune satellite cell fate in dystrophic skeletal muscle of mdx mice.
PLoS genetics
Madaro L,Torcinaro A,De Bardi M,Contino FF,Pelizzola M,Diaferia GR,Imeneo G,Bouchè M,Puri PL,De Santa F
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Tue Oct 01 00:00:00 EDT 2019
TGFβ-induced degradation of TRAF3 in mesenchymal progenitor cells causes age-related osteoporosis.
Nature communications
Li J,Ayoub A,Xiu Y,Yin X,Sanders JO,Mesfin A,Xing L,Yao Z,Boyce BF
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Wed Jun 26 00:00:00 EDT 2019
Excessive exosome release is the pathogenic pathway linking a lysosomal deficiency to generalized fibrosis.
Science advances
van de Vlekkert D,Demmers J,Nguyen XX,Campos Y,Machado E,Annunziata I,Hu H,Gomero E,Qiu X,Bongiovanni A,Feghali-Bostwick CA,d'Azzo A
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Mon Jul 01 00:00:00 EDT 2019
The microRNAs miR-204 and miR-211 maintain joint homeostasis and protect against osteoarthritis progression.
Nature communications
Huang J,Zhao L,Fan Y,Liao L,Ma PX,Xiao G,Chen D
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Fri Jun 28 00:00:00 EDT 2019
Procr-expressing progenitor cells are responsible for murine ovulatory rupture repair of ovarian surface epithelium.
Nature communications
Wang J,Wang D,Chu K,Li W,Zeng YA
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu Oct 31 00:00:00 EDT 2019
Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy.
Nature communications
Welc SS,Flores I,Wehling-Henricks M,Ramos J,Wang Y,Bertoni C,Tidball JG
15-5981 was used in Flow cytometry/Cell sorting to study the effect of expression of a therapeutic transgene in leukocyte progenitors that invade muscle on selective and timely delivery to diseased muscle.
Wed Jun 26 00:00:00 EDT 2019
Novel evidence that extracellular nucleotides and purinergic signaling induce innate immunity-mediated mobilization of hematopoietic stem/progenitor cells.
Leukemia
Adamiak M,Bujko K,Cymer M,Plonka M,Glaser T,Kucia M,Ratajczak J,Ulrich H,Abdel-Latif A,Ratajczak MZ
15-5981 was used in Flow cytometry/Cell sorting to demonstrate that ATP and its metabolite adenosine have an important role in the egress of hematopoietic stem progenitor cells from bone marrow niches into peripheral blood.
Sat Sep 01 00:00:00 EDT 2018
PDGF is a potent initiator of bone formation in a tissue engineered model of pathological ossification.
Journal of tissue engineering and regenerative medicine
Davies OG,Grover LM,Lewis MP,Liu Y
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Mon Jan 01 00:00:00 EST 2018
The H3K4 methyltransferase Setd1b is essential for hematopoietic stem and progenitor cell homeostasis in mice.
eLife
Schmidt K,Zhang Q,Tasdogan A,Petzold A,Dahl A,Arneth BM,Slany R,Fehling HJ,Kranz A,Stewart AF,Anastassiadis K
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Tue Jun 19 00:00:00 EDT 2018
Tracking of Adipose-Derived Mesenchymal Stromal/Stem Cells in a Model of Cisplatin-Induced Acute Kidney Injury: Comparison of Bioluminescence Imaging versus qRT-PCR.
International journal of molecular sciences
Schubert R,Sann J,Frueh JT,Ullrich E,Geiger H,Baer PC
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Wed Aug 29 00:00:00 EDT 2018
Differential requirement of kindlin-3 for T cell progenitor homing to the non-vascularized and vascularized thymus.
eLife
Moretti FA,Klapproth S,Ruppert R,Margraf A,Weber J,Pick R,Scheiermann C,Sperandio M,Fässler R,Moser M
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu Sep 06 00:00:00 EDT 2018
HMGB2 is a novel adipogenic factor that regulates ectopic fat infiltration in skeletal muscles.
Scientific reports
Lee D,Taniguchi N,Sato K,Choijookhuu N,Hishikawa Y,Kataoka H,Morinaga H,Lotz M,Chosa E
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Mon Jun 25 00:00:00 EDT 2018
Stem cell factor is selectively secreted by arterial endothelial cells in bone marrow.
Nature communications
Xu C,Gao X,Wei Q,Nakahara F,Zimmerman SE,Mar J,Frenette PS
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Fri Jun 22 00:00:00 EDT 2018
RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells.
The Journal of biological chemistry
Ge J,Burnier L,Adamopoulou M,Kwa MQ,Schaks M,Rottner K,Brakebusch C
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Fri Jun 15 00:00:00 EDT 2018
Bone marrow-derived immature myeloid cells are a main source of circulating suPAR contributing to proteinuric kidney disease.
Nature medicine
Hahm E,Wei C,Fernandez I,Li J,Tardi NJ,Tracy M,Wadhwani S,Cao Y,Peev V,Zloza A,Lusciks J,Hayek SS,O'Connor C,Bitzer M,Gupta V,Sever S,Sykes DB,Scadden DT,Reiser J
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Sun Jan 01 00:00:00 EST 2017
FOXP1 controls mesenchymal stem cell commitment and senescence during skeletal aging.
The Journal of clinical investigation
Li H,Liu P,Xu S,Li Y,Dekker JD,Li B,Fan Y,Zhang Z,Hong Y,Yang G,Tang T,Ren Y,Tucker HO,Yao Z,Guo X
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Mon Apr 03 00:00:00 EDT 2017
GATA4-dependent organ-specific endothelial differentiation controls liver development and embryonic hematopoiesis.
The Journal of clinical investigation
Géraud C,Koch PS,Zierow J,Klapproth K,Busch K,Olsavszky V,Leibing T,Demory A,Ulbrich F,Diett M,Singh S,Sticht C,Breitkopf-Heinlein K,Richter K,Karppinen SM,Pihlajaniemi T,Arnold B,Rodewald HR,Augustin HG,Schledzewski K,Goerdt S
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2017
Induced p53 loss in mouse luminal cells causes clonal expansion and development of mammary tumours.
Nature communications
Tao L,Xiang D,Xie Y,Bronson RT,Li Z
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Mon Feb 13 00:00:00 EST 2017
Mutant U2AF1-expressing cells are sensitive to pharmacological modulation of the spliceosome.
Nature communications
Shirai CL,White BS,Tripathi M,Tapia R,Ley JN,Ndonwi M,Kim S,Shao J,Carver A,Saez B,Fulton RS,Fronick C,O'Laughlin M,Lagisetti C,Webb TR,Graubert TA,Walter MJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Mon Jan 09 00:00:00 EST 2017
Microgrooved-surface topography enhances cellular division and proliferation of mouse bone marrow-derived mesenchymal stem cells.
PloS one
Chaudhary JK,Rath PC
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu Oct 19 00:00:00 EDT 2017
Zoledronate suppressed angiogenesis and osteogenesis by inhibiting osteoclasts formation and secretion of PDGF-BB.
PloS one
Gao SY,Zheng GS,Wang L,Liang YJ,Zhang SE,Lao XM,Li K,Liao GQ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Mon Sep 18 00:00:00 EDT 2017
Inducible Nitric Oxide Synthase (iNOS) Is a Novel Negative Regulator of Hematopoietic Stem/Progenitor Cell Trafficking.
Stem cell reviews and reports
Adamiak M,Abdelbaset-Ismail A,Moore JB,Zhao J,Abdel-Latif A,Wysoczynski M,Ratajczak MZ
15-5981 was used in Flow cytometry/Cell sorting to indicate that inducible nitric oxide synthetase is a negative regulator of hematopoietic cell migration.
Wed Feb 01 00:00:00 EST 2017
Signaling of the Complement Cleavage Product Anaphylatoxin C5a Through C5aR (CD88) Contributes to Pharmacological Hematopoietic Stem Cell Mobilization.
Stem cell reviews and reports
Bujko K,Rzeszotek S,Hoehlig K,Yan J,Vater A,Ratajczak MZ
15-5981 was used in Flow cytometry/Cell sorting to show mice deficient in C5aR, and thus unable to mediate signaling of the complement cleavage product anaphylatoxin C5, have poor mobilization of hematopoietic stem/progenitor cells.
Fri Dec 01 00:00:00 EST 2017
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.
Cell
Damgaard RB,Walker JA,Marco-Casanova P,Morgan NV,Titheradge HL,Elliott PR,McHale D,Maher ER,McKenzie ANJ,Komander D
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu Aug 25 00:00:00 EDT 2016
Evidence that a lipolytic enzyme--hematopoietic-specific phospholipase C-β2--promotes mobilization of hematopoietic stem cells by decreasing their lipid raft-mediated bone marrow retention and increasing the promobilizing effects of granulocytes.
Leukemia
Adamiak M,Poniewierska-Baran A,Borkowska S,Schneider G,Abdelbaset-Ismail A,Suszynska M,Abdel-Latif A,Kucia M,Ratajczak J,Ratajczak MZ
15-5981 was used in Flow cytometry/Cell sorting to report the role of hematopoietic cell-specific phospholipase C-β2 (PLC-β2) in the pharmacological mobilization of hematopoietic stem/progenitor cells (HSPCs).
Fri Apr 01 00:00:00 EDT 2016
Hedgehog-driven myogenic tumors recapitulate skeletal muscle cellular heterogeneity.
Experimental cell research
Hettmer S,Lin MM,Tchessalova D,Tortorici SJ,Castiglioni A,Desai T,Mao J,McMahon AP,Wagers AJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2016
Identification of an epidermal keratinocyte AMPA glutamate receptor involved in dermatopathies associated with sensory abnormalities.
Pain reports
Cabañero D,Irie T,Celorrio M,Trousdale C,Owens DM,Virley D,Albrecht PJ,Caterina MJ,Rice FL,Morón JA
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu Sep 01 00:00:00 EDT 2016
KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis.
Nature medicine
Shankman LS,Gomez D,Cherepanova OA,Salmon M,Alencar GF,Haskins RM,Swiatlowska P,Newman AA,Greene ES,Straub AC,Isakson B,Randolph GJ,Owens GK
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2015
Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity.
Nature cell biology
Jeffery E,Church CD,Holtrup B,Colman L,Rodeheffer MS
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Wed Apr 01 00:00:00 EDT 2015
CD93 Marks a Non-Quiescent Human Leukemia Stem Cell Population and Is Required for Development of MLL-Rearranged Acute Myeloid Leukemia.
Cell stem cell
Iwasaki M,Liedtke M,Gentles AJ,Cleary ML
15-5981 was used in Flow cytometry/Cell sorting to study how CD93 expression may indicate leukaemia initiating stem cells that have a MLL gene rearrangement.
Thu Oct 01 00:00:00 EDT 2015
Cis-regulatory mechanisms governing stem and progenitor cell transitions.
Science advances
Johnson KD,Kong G,Gao X,Chang YI,Hewitt KJ,Sanalkumar R,Prathibha R,Ranheim EA,Dewey CN,Zhang J,Bresnick EH
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Tue Sep 01 00:00:00 EDT 2015
Paracrine Met signaling triggers epithelial-mesenchymal transition in mammary luminal progenitors, affecting their fate.
eLife
Di-Cicco A,Petit V,Chiche A,Bresson L,Romagnoli M,Orian-Rousseau V,Vivanco Md,Medina D,Faraldo MM,Glukhova MA,Deugnier MA
15-5981 was used in Flow cytometry/Cell sorting to indicate that paracrine Met signaling can control the function of luminal progenitors and modulate their fate during mammary development and tumorigenesis.
Mon Jul 13 00:00:00 EDT 2015
Mouse bone marrow-derived mesenchymal stem cells inhibit leukemia/lymphoma cell proliferation in vitro and in a mouse model of allogeneic bone marrow transplant.
International journal of molecular medicine
Song N,Gao L,Qiu H,Huang C,Cheng H,Zhou H,Lv S,Chen L,Wang J
15-5981 was used in Flow cytometry/Cell sorting to determine that MSCs may be safe and effective when used in allogeneic BMT for the treatment of haemotological malignancies.
Wed Jul 01 00:00:00 EDT 2015
Cellular and molecular characterization of human cardiac stem cells reveals key features essential for their function and safety.
Stem cells and development
Vahdat S,Mousavi SA,Omrani G,Gholampour M,Sotoodehnejadnematalahi F,Ghazizadeh Z,Gharechahi J,Baharvand H,Salekdeh GH,Aghdami N
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Mon Jun 15 00:00:00 EDT 2015
Multi-Drug Resistance ABC Transporter Inhibition Enhances Murine Ventral Prostate Stem/Progenitor Cell Differentiation.
Stem cells and development
Samant MD,Jackson CM,Felix CL,Jones AJ,Goodrich DW,Foster BA,Huss WJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Fri May 15 00:00:00 EDT 2015
Limited miR-17-92 overexpression drives hematologic malignancies.
Leukemia research
Danielson LS,Reavie L,Coussens M,Davalos V,Castillo-Martin M,Guijarro MV,Coffre M,Cordon-Cardo C,Aifantis I,Ibrahim S,Liu C,Koralov SB,Hernando E
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Sun Mar 01 00:00:00 EST 2015
Cardiogenic genes expressed in cardiac fibroblasts contribute to heart development and repair.
Circulation research
Furtado MB,Costa MW,Pranoto EA,Salimova E,Pinto AR,Lam NT,Park A,Snider P,Chandran A,Harvey RP,Boyd R,Conway SJ,Pearson J,Kaye DM,Rosenthal NA
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Fri Apr 25 00:00:00 EDT 2014
WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner.
The Journal of experimental medicine
Xia P,Wang S,Huang G,Zhu P,Li M,Ye B,Du Y,Fan Z
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Mon Sep 22 00:00:00 EDT 2014
Overexpressing sonic hedgehog peptide restores periosteal bone formation in a murine bone allograft transplantation model.
Molecular therapy : the journal of the American Society of Gene Therapy
Huang C,Tang M,Yehling E,Zhang X
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Sat Feb 01 00:00:00 EST 2014
Cell-autonomous heparanase modulates self-renewal and migration in bone marrow-derived mesenchymal stem cells.
Journal of biomedical science
Cheng CC,Lee YH,Lin SP,Huangfu WC,Liu IH
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu Mar 13 00:00:00 EDT 2014
Recruitment of bone marrow-derived cells to periodontal tissue defects.
Frontiers in cell and developmental biology
Kimura Y,Komaki M,Iwasaki K,Sata M,Izumi Y,Morita I
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Mon Nov 03 00:00:00 EST 2014
Evidence for Transfer of Membranes from Mesenchymal Stem Cells to HL-1 Cardiac Cells.
Stem cells international
Boomsma RA,Geenen DL
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Wed Oct 08 00:00:00 EDT 2014
Amniotic fluid stem cells prevent follicle atresia and rescue fertility of mice with premature ovarian failure induced by chemotherapy.
PloS one
Xiao GY,Liu IH,Cheng CC,Chang CC,Lee YH,Cheng WT,Wu SC
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu May 28 00:00:00 EDT 2015
Validation of the effects of TGF-β1 on tumor recurrence and prognosis through tumor retrieval and cell mechanical properties.
Cancer cell international
Wu TH,Chou YW,Chiu PH,Tang MJ,Hu CW,Yeh ML
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Mon Mar 03 00:00:00 EST 2014
HIF prolyl hydroxylase 2 (PHD2) is a critical regulator of hematopoietic stem cell maintenance during steady-state and stress.
Blood
Singh RP,Franke K,Kalucka J,Mamlouk S,Muschter A,Gembarska A,Grinenko T,Willam C,Naumann R,Anastassiadis K,Stewart AF,Bornstein S,Chavakis T,Breier G,Waskow C,Wielockx B
15-5981 was used in Flow cytometry/Cell sorting to study the role of PHD2 in HSC compartment maintenance.
Thu Jun 27 00:00:00 EDT 2013
A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL).
Disease models & mechanisms
Carofino BL,Ayanga B,Justice MJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Fri Nov 01 00:00:00 EDT 2013
Enhancing T lineage production in aged mice: a novel function of Foxn1 in the bone marrow niche.
Journal of immunology (Baltimore, Md. : 1950)
Zook EC,Zhang S,Gerstein RM,Witte PL,Le PT
15-5981 was used in Flow cytometry/Cell sorting to report that Foxn1 is expressed in wild-type BM and overexpressed in Foxn1Tg.
Sun Dec 01 00:00:00 EST 2013
A non-redundant function of cyclin E1 in hematopoietic stem cells.
Cell cycle (Georgetown, Tex.)
Campaner S,Viale A,De Fazio S,Doni M,De Franco F,D'Artista L,Sardella D,Pelicci PG,Amati B
15-5981 was used in Flow cytometry/Cell sorting to support a role for cyclin E1 in controlling the exit from quiescence in hematopoietic stem cells.
Sun Dec 01 00:00:00 EST 2013
Lunatic fringe deficiency cooperates with the Met/Caveolin gene amplicon to induce basal-like breast cancer.
Cancer cell
Xu K,Usary J,Kousis PC,Prat A,Wang DY,Adams JR,Wang W,Loch AJ,Deng T,Zhao W,Cardiff RD,Yoon K,Gaiano N,Ling V,Beyene J,Zacksenhaus E,Gridley T,Leong WL,Guidos CJ,Perou CM,Egan SE
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Tue May 15 00:00:00 EDT 2012
Concomitant inactivation of Rb and E2f8 in hematopoietic stem cells synergizes to induce severe anemia.
Blood
Hu T,Ghazaryan S,Sy C,Wiedmeyer C,Chang V,Wu L
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu May 10 00:00:00 EDT 2012
Cis-element mutated in GATA2-dependent immunodeficiency governs hematopoiesis and vascular integrity.
The Journal of clinical investigation
Johnson KD,Hsu AP,Ryu MJ,Wang J,Gao X,Boyer ME,Liu Y,Lee Y,Calvo KR,Keles S,Zhang J,Holland SM,Bresnick EH
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Mon Oct 01 00:00:00 EDT 2012
Thymus-autonomous T cell development in the absence of progenitor import.
The Journal of experimental medicine
Martins VC,Ruggiero E,Schlenner SM,Madan V,Schmidt M,Fink PJ,von Kalle C,Rodewald HR
15-5981 was used in Flow cytometry/Cell sorting to characterise the previously unrecognised capacity of the thymus to sustain T cell development during bone marrow progenitor deprivation.
Mon Jul 30 00:00:00 EDT 2012
CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and stem cell exhaustion.
The EMBO journal
Gu P,Min JN,Wang Y,Huang C,Peng T,Chai W,Chang S
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Wed May 16 00:00:00 EDT 2012
Induction of cardiac myogenic lineage development differs between mesenchymal and satellite cells and is accelerated by bone morphogenetic protein-4.
Journal of molecular and cellular cardiology
Grajales L,García J,Geenen DL
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Sat Sep 01 00:00:00 EDT 2012
Essential roles for Pot1b in HSC self-renewal and survival.
Blood
Wang Y,Shen MF,Chang S
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2011
The earliest intrathymic precursors of CD8α(+) thymic dendritic cells correspond to myeloid-type double-negative 1c cells.
European journal of immunology
Luche H,Ardouin L,Teo P,See P,Henri S,Merad M,Ginhoux F,Malissen B
15-5981 was used in Flow cytometry/Cell sorting to provide evidence that myeloid-restricted progenitors generate the whole constellation of DCs present in the body, including the thymus.
Mon Aug 01 00:00:00 EDT 2011
CD24-positive cells from normal adult mouse liver are hepatocyte progenitor cells.
Stem cells and development
Qiu Q,Hernandez JC,Dean AM,Rao PH,Darlington GJ
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu Dec 01 00:00:00 EST 2011
A high omega-3 fatty acid diet has different effects on early and late stage myeloid progenitors.
Lipids
Varney ME,Buchanan JT,Dementieva Y,Hardman WE,Sollars VE
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Sat Jan 01 00:00:00 EST 2011
Delayed enrichment of mesenchymal cells promotes cardiac lineage and calcium transient development.
Journal of molecular and cellular cardiology
Grajales L,García J,Banach K,Geenen DL
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Thu Apr 01 00:00:00 EDT 2010
Additive and global functions of HoxA cluster genes in mesoderm derivatives.
Developmental biology
Di-Poï N,Koch U,Radtke F,Duboule D
15-5981 was used in Flow cytometry/Cell sorting to report that mutant mice lacking the entire HoxA cluster in mesodermal lineages display the expected spectrum of postnatal respiratory, cardiac and urogenital defects, previously reported for single gene mutations.
Sat May 15 00:00:00 EDT 2010
Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells.
Cell stem cell
Le Grand F,Jones AE,Seale V,Scimè A,Rudnicki MA
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Fri Jun 05 00:00:00 EDT 2009
Impaired mobilization of hematopoietic stem/progenitor cells in C5-deficient mice supports the pivotal involvement of innate immunity in this process and reveals novel promobilization effects of granulocytes.
Leukemia
Lee HM,Wu W,Wysoczynski M,Liu R,Zuba-Surma EK,Kucia M,Ratajczak J,Ratajczak MZ
15-5981 was used in Flow cytometry/Cell sorting to examine the central role of innate immunity in the mobilisation of haematopoietic stem/progenitor cells.
Sun Nov 01 00:00:00 EDT 2009
A differentiation pathway for B1 cells in adult bone marrow.
Proceedings of the National Academy of Sciences of the United States of America
Esplin BL,Welner RS,Zhang Q,Borghesi LA,Kincade PW
15-5981 was used in Flow cytometry/Cell sorting to investigate the developmental origins of the B1-specified progenitor population in adult bone marrow.
Tue Apr 07 00:00:00 EDT 2009
A possible contribution of retinoids to regulation of fetal B lymphopoiesis.
European journal of immunology
Chen X,Welner RS,Kincade PW
15-5981 was used in Flow cytometry/Cell sorting to determine that retinoids may partially account for rapid differentiation in foetal life, but not for all unique features of foetal progenitors.
Tue Sep 01 00:00:00 EDT 2009
c-Myb is required for pro-B cell differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Fahl SP,Crittenden RB,Allman D,Bender TP
15-5981 was used in Flow cytometry/Cell sorting to demonstrate that c-Myb is absolutely required for the survival and differentiation of CD19(+) B-lineage cells.
Sun Nov 01 00:00:00 EDT 2009
Reporter gene-expressing bone marrow-derived stromal cells are immune-tolerated following implantation in the central nervous system of syngeneic immunocompetent mice.
BMC biotechnology
Bergwerf I,De Vocht N,Tambuyzer B,Verschueren J,Reekmans K,Daans J,Ibrahimi A,Van Tendeloo V,Chatterjee S,Goossens H,Jorens PG,Baekelandt V,Ysebaert D,Van Marck E,Berneman ZN,Linden AV,Ponsaerts P
Published figure using Ly-6A/E (Sca-1) monoclonal antibody (Product # 15-5981-82) in Flow Cytometry
Wed Jan 07 00:00:00 EST 2009
Lymphoid precursors are directed to produce dendritic cells as a result of TLR9 ligation during herpes infection.
Blood
Welner RS,Pelayo R,Nagai Y,Garrett KP,Wuest TR,Carr DJ,Borghesi LA,Farrar MA,Kincade PW
15-5981 was used in Flow cytometry/Cell sorting to show that common lymphoid progenitors from mice with active HSV-1 infection are biased to dendritic cell differentiation.
Sat Nov 01 00:00:00 EDT 2008
E47 controls the developmental integrity and cell cycle quiescence of multipotential hematopoietic progenitors.
Journal of immunology (Baltimore, Md. : 1950)
Yang Q,Kardava L,St Leger A,Martincic K,Varnum-Finney B,Bernstein ID,Milcarek C,Borghesi L
15-5981 was used in Flow cytometry/Cell sorting to show E47 controls the developmental integrity and cell cycle quiescence of hematopoietic progenitors.
Sat Nov 01 00:00:00 EDT 2008
Contrasting responses of lymphoid progenitors to canonical and noncanonical Wnt signals.
Journal of immunology (Baltimore, Md. : 1950)
Malhotra S,Baba Y,Garrett KP,Staal FJ,Gerstein R,Kincade PW
15-5981 was used in Flow cytometry/Cell sorting to learn whether, and how, particular stages of B lymphopoiesis are responsive to Wnt family ligands.
Mon Sep 15 00:00:00 EDT 2008
Polysialic acid, a glycan with highly restricted expression, is found on human and murine leukocytes and modulates immune responses.
Journal of immunology (Baltimore, Md. : 1950)
Drake PM,Nathan JK,Stock CM,Chang PV,Muench MO,Nakata D,Reader JR,Gip P,Golden KP,Weinhold B,Gerardy-Schahn R,Troy FA,Bertozzi CR
15-5981 was used in Flow cytometry/Cell sorting to investigate the expression and possible function of polysialic acid in the immune system.
Sat Nov 15 00:00:00 EST 2008
Polysialic acid, a glycan with highly restricted expression, is found on human and murine leukocytes and modulates immune responses.
Journal of immunology (Baltimore, Md. : 1950)
Drake PM,Nathan JK,Stock CM,Chang PV,Muench MO,Nakata D,Reader JR,Gip P,Golden KP,Weinhold B,Gerardy-Schahn R,Troy FA,Bertozzi CR
15-5981 was used in Flow cytometry/Cell sorting to investigate the expression and possible function of polysialic acid in the immune system.
Sat Nov 15 00:00:00 EST 2008
MN1 overexpression induces acute myeloid leukemia in mice and predicts ATRA resistance in patients with AML.
Blood
Heuser M,Argiropoulos B,Kuchenbauer F,Yung E,Piper J,Fung S,Schlenk RF,Dohner K,Hinrichsen T,Rudolph C,Schambach A,Baum C,Schlegelberger B,Dohner H,Ganser A,Humphries RK
15-5981 was used in Flow cytometry/Cell sorting to study the effect of MN1 overexpression in mice and human patients with acute myeloid leukemia and predict ATRA resistance.
Sat Sep 01 00:00:00 EDT 2007
Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment.
Immunity
Nagai Y,Garrett KP,Ohta S,Bahrun U,Kouro T,Akira S,Takatsu K,Kincade PW
15-5981 was used in Flow cytometry/Cell sorting to investigate the expression of toll-like receptors on different hematopoietic stem cells and the mechanism by which they stimulate innate immune system replenishment.
Thu Jun 01 00:00:00 EDT 2006
The order of expression of transcription factors directs hierarchical specification of hematopoietic lineages.
Genes & development
Iwasaki H,Mizuno S,Arinobu Y,Ozawa H,Mori Y,Shigematsu H,Takatsu K,Tenen DG,Akashi K
15-5981 was used in Flow cytometry/Cell sorting to show that the expression timing of GATA-2 and CCAAT enhancer-binding protein alpha can differentially control their lineage commitment.
Wed Nov 01 00:00:00 EST 2006
Primitive lymphoid progenitors in bone marrow with T lineage reconstituting potential.
Journal of immunology (Baltimore, Md. : 1950)
Perry SS,Welner RS,Kouro T,Kincade PW,Sun XH
15-5981 was used in Flow cytometry/Cell sorting to determine which T cell subset colonise the thymus under normal circumstances, by side by side comparison of the three categories of bone marrow cells with T lymphopoietic potential.
Fri Sep 01 00:00:00 EDT 2006
Hmgb3 deficiency deregulates proliferation and differentiation of common lymphoid and myeloid progenitors.
Blood
Nemeth MJ,Cline AP,Anderson SM,Garrett-Beal LJ,Bodine DM
15-5981 was used in Flow cytometry/Cell sorting to examine the role of Hmgb3 in adult haematopoiesis.
Sat Jan 15 00:00:00 EST 2005
Identification of eosinophil lineage-committed progenitors in the murine bone marrow.
The Journal of experimental medicine
Iwasaki H,Mizuno S,Mayfield R,Shigematsu H,Arinobu Y,Seed B,Gurish MF,Takatsu K,Akashi K
15-5981 was used in Flow cytometry/Cell sorting to show that newly identified eosinophil lineage-committed progenitors could be the cellular target in the treatment of a variety of disorders mediated by eosinophils.
Mon Jun 20 00:00:00 EDT 2005
Beta-catenin is dispensable for hematopoiesis and lymphopoiesis.
The Journal of experimental medicine
Cobas M,Wilson A,Ernst B,Mancini SJ,MacDonald HR,Kemler R,Radtke F
15-5981 was used in Flow cytometry/Cell sorting to investigate an essential role for beta-catenin during hematopoiesis and lymphopoiesis.
Mon Jan 19 00:00:00 EST 2004
