|Tested species reactivity||Mouse|
|Published species reactivity||Mouse, Not Applicable|
|Host / Isotype||Rat / IgG2b|
|Immunogen||Normal murine bone marrow cells|
|Storage buffer||PBS with 4mg/ml BSA|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C, store in dark|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Granulocytes are a category of white blood cells characterised by the presence of granules in their cytoplasm. They are also called polymorphonuclear leukocytes (PMN or PML) because of the varying shapes of the nucleus, which is usually lobed into three segments. In common parlance, the term polymorphonuclear leukocyte often refers specifically to neutrophil granulocytes, the most abundant of the granulocytes. Granulocytes or PMN are released from the bone marrow by the regulatory complement proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Immune quiescence of the brain is set by astroglial connexin 43.
RM3030 was used in immunohistochemistry - paraffin section to study the role of astroglial cx43 in immune quiescence of the brain
|Boulay AC,Mazeraud A,Cisternino S,Saubaméa B,Mailly P,Jourdren L,Blugeon C,Mignon V,Smirnova M,Cavallo A,Ezan P,Avé P,Dingli F,Loew D,Vieira P,Chrétien F,Cohen-Salmon M||The Journal of neuroscience : the official journal of the Society for Neuroscience (35:4427)||2015|
Ectopic TBX1 suppresses thymic epithelial cell differentiation and proliferation during thymus organogenesis.
RM3030 was used in flow cytometry to assess the contribution of Tbx1 to thymus and parathyroid development
|Reeh KA,Cardenas KT,Bain VE,Liu Z,Laurent M,Manley NR,Richie ER||Development (Cambridge, England) (141:2950)||2014|
|Not Applicable||Not Cited||
IL-1¿/IL-1R1 expression in chronic obstructive pulmonary disease and mechanistic relevance to smoke-induced neutrophilia in mice.
RM3030 was used in flow cytometry to review cellular and molecular mechanisms that contribute to chronic obstructive pulmonary disease pathogenesis
|Botelho FM,Bauer CM,Finch D,Nikota JK,Zavitz CC,Kelly A,Lambert KN,Piper S,Foster ML,Goldring JJ,Wedzicha JA,Bassett J,Bramson J,Iwakura Y,Sleeman M,Kolbeck R,Coyle AJ,Humbles AA,Stämpfli MR||PloS one (6:null)||2011|
MHC class I family proteins retard systemic lupus erythematosus autoimmunity and B cell lymphomagenesis.
RM3030 was used in flow cytometry to determine the contributions of individual MHC class I family members to autoimmunity in two mouse models.
|McPhee CG,Sproule TJ,Shin DM,Bubier JA,Schott WH,Steinbuck MP,Avenesyan L,Morse HC,Roopenian DC||Journal of immunology (Baltimore, Md. : 1950) (187:4695)||2011|
Consequences of the combined loss of BOK and BAK or BOK and BAX.
RM3030 was used in flow cytometry to determine if Bok and Bax have any functional redundancy controlling apoptosis using knock out mice.
|Ke F,Bouillet P,Kaufmann T,Strasser A,Kerr J,Voss AK||Cell death and disease (4:null)||2013|
Granulocyte-dendritic cell unbalance in the non-obese diabetic mice.
RM3030 was used in flow cytometry to investigate DCs in non-obese diabetic mice.
|Morin J,Chimènes A,Boitard C,Berthier R,Boudaly S||Cellular immunology (223:13)||2003|
Comparison of erythropoietic response to androgen in young and old senescence accelerated mice.
RM3030 was used in flow cytometry to test if the functional capacity of hemopoietic progenitor cells and the micro-environment of aged and young mice are identical.
|Saitoh T,Morimoto K,Kumagai T,Tsuboi I,Aikawa S,Horie T||Mechanisms of ageing and development (109:125)||1999|