This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
MA5-15329 targets LYN in indirect ELISA, WB applications and shows reactivity with Human samples.
The MA5-15329 immunogen is purified recombinant fragment of LYN expressed in E. Coli.
MA5-15329 detects LYN which has a predicted molecular weight of approximately 56kDa.
Lyn proto oncogene (Lcl/Yes related novel protein tyrosine kinase) is encoded by the Lyn gene located on chromosome 8 in humans and belongs to the Src family kinase. It is a non-receptor tyrosine kinase that acts as a mediator in transducing cellular signaling. The most well studied expression of Lyn is in hematopoietic cell types, both lymphoid and myeloid cells with exclusion in T lymphocytes. It has also been observed that Lyn plays diverse roles such as in regulation of B cell receptor signaling, mast cell signaling and Epithelial - Mesenchymal Transition (EMT).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ26625; Lck/Yes-related novel protein tyrosine kinase; p53Lyn; p56Lyn; Tyrosine-protein kinase Lyn; V-yes-1 Yamaguchi sarcoma viral related oncogene homolog
Gene Aliases: JTK8; LYN; p53Lyn; p56Lyn
UniProt ID: (Human) P07948
Entrez Gene ID: (Human) 4067