|Western Blot (WB)||10-15 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to human lysophospholipid phosphatase 3.|
|Purification||Ammonium sulfate precipitation|
|Contains||0.08% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
A suggested positive control for this product is transfected HEK-293 cells.
Phosphatidic acid phosphatase type 2 (PAP2) was originally identified as a plasma membrane enzyme that catalyses the dephosphorylation of the putative second messenger, phosphatidic acid (PA) to diacylglycerol (DG). Subsequently, multiple isoforms of PAP2 were cloned [2-5]. It was found that these enzymes dephosphorylate a number of lipid phosphates in vitro other than PA, including the potent bioactive lipids, lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P). Therefore, they have been renamed lipid phosphate phosphatases (LPPs). Currently, there are four members of this family called LPP1, LPP1a, LPP2 and LPP3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Dri42; Lipid phosphate phosphohydrolase 3; LPP3; MGC15306; PAP-2b; PAP2 beta; PAP2-b; PAP2-beta; Phosphatidate phosphohydrolase type 2b; Phosphatidic acid phosphatase 2b; phosphatidic acid phosphatase type 2B; Phospholipid phosphatase 3; type-2 phosphatidic acid phosphatase-beta; vascular endothelial growth factor and type I collagen inducible; Vascular endothelial growth factor and type I collagen-inducible protein; VCIP
Gene Aliases: Dri42; LPP3; PAP2B; PLPP3; PPAP2B; VCIP
UniProt ID: (Human) O14495
Entrez Gene ID: (Human) 8613
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