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Staining of mouse thioglycolate-elicited peritoneal exudate cells with Anti-Mouse CD11b eFluor® 450 and 0.03 ug of Rat IgG2a K Isotype Control PE (top) or 0.03 ug of Anti- Mouse CD115 (c-fms) PE (bottom, A16392). Cells in the large scatter population were used for analysis.
|Tested species reactivity||Mouse|
|Host / Isotype||Rat / IgG2a, kappa|
|Storage buffer||proprietary buffer|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
CSF1R is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CSF-1R, AI323359, Fms, Fim-2, M-CSF-R, Csfmr, CD115, M-CSFR
CSF-1 receptor, CSF-1-R, c-fms, macrophage colony-stimulating factor 1 receptor, proto-oncogene c-Fms, proto-oncogene fms, CSF1R, colony stimulating factor 1 receptor, C-FMS, CD115, CSFR, FIM2, FMS, CD115 antigen, FMS proto-oncogene, McDonough feline sarcoma viral v-fms oncogene homolog, macrophage colony stimulating factor I receptor