This antibody can be used as a capture antibody in a Sandwich ELISA with detection antibody MA1-19438.
CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein. CD5 is present on all mature T-lymphocytes, on most of thymocytes and on many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor in regulating T-cell proliferation. CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by many T cell leukemia, lymphomas, and activated T cells. Diseases associated with CD5 dysfunction include thymus cancer and Richter's Syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD5; CD5 antigen (p56-62); CD5 antigen p56-62; Lymphocyte antigen T1/Leu-1; T-cell surface glycoprotein CD5
Gene Aliases: CD5; LEU1; T1
UniProt ID: (Human) P06127
Entrez Gene ID: (Human) 921