Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
MA1-21212 detects Tissue factor (FITC) in Human samples. Does not cross react with rabbit.
MA1-21212 has been successfully used in ELISA and Immunofluorescence procedures.
MA1-21212 immunogen corresponds to Full length purified human native protein.
Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze/thaw cycles.
This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD142; Coagulation factor III; coagulation factor III (thromboplastin, tissue factor); TF; Thromboplastin; Tissue factor
Gene Aliases: F3
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