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Invitrogen
MA1-21807 detects Type II Collagen in Human, Mouse and Chicken samples.
MA1-21807 has been successfully used in Immunofluorescence and western blot procedures. Positive control:cartilage
MA1-21807 immunogen corresponds to A purified preparation of lathyritic type II collagen from embryonic chicken sternum.
COL2A1 is the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: alpha 1 type II procollagen; alpha 1 type IIA collagen; alpha collagen type II; Alpha-1 type II collagen; arthroophthalmopathy, progressive (Stickler syndrome); cartilage collagen; CGA; Chondrocalcin; Collagen 2; Collagen alpha-1(II) chain; collagen II, alpha-1 polypeptide; collagen, type II, alpha 1; collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital); disproportionate micromelia; MGC131516; procollagen alpha 1(II); procollagen, type II, alpha 1; type II collagen
Gene Aliases: COL2A1
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