MA1-25479 detects Metallothionein from human, mouse, fish, equine, rat, and rabbit samples.
MA1-25479 has been successfully used in Western blot and Immunohistochemistry procedures. A band of approximately 15 kDa is detected.
The MA1-25479 immunogen is full length protein from cross linked rabbit liver MT1 and MT2.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Metallothioneins (MTs) are a family of low molecular weight, heavy metal-binding proteins characterized by a high cysteine content and lack of aromatic amino acids. MTs bind 7 to 12 heavy metal atoms per molecule of protein. They are ubiquitous in the animal and plant kingdoms and are also found in prokaryotes. In mammals, the cysteine residues are absolutely conserved and serve to coordinate heavy metal atoms such as zinc, cadmium, and copper via mercaptide linkages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: metallothionein 1A (functional); metallothionein 1S; Metallothionein-1; Metallothionein-1A; Metallothionein-I; Metallothionein-IA; MT-1; MT-1A; MT-I; MT-IA; uncharacterized LOC100343802
Gene Aliases: Mt; Mt-1; MT-I; MT1; MT1A; MT1S; MTC