MA5-14576 targets Alpha methylacyl-CoA-racemase in WB, IF and IHC (P) applications and shows reactivity with Human samples.
The MA5-14576 immunogen is human p504s/AMACR polypeptide.
Alpha methylacyl-CoA-racemase (AMACR), also known as p504s is an enzyme involved in the metabolism of branched-chain fatty acids. p504s is expressed in various normal tissues and carcinomas, while it is overexpressed over 30-fold in prostate carcinoma compared to benign glandular tissues1. When p504s is overexpressed in atypical glands without basal cells, it establishes a diagnosis of prostatic carcinoma. High-grade prostatic intraepithelial neoplasia, atypical adenomatous hyperplasia and urothelial carcinoma may also express p504s.
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Protein Aliases: 2-methylacyl-CoA racemase; Alpha-methylacyl-CoA racemase
Gene Aliases: AMACR; AMACRD; CBAS4; RACE; RM
UniProt ID: (Human) Q9UHK6
Entrez Gene ID: (Human) 23600