MA5-17188 targets THPO in FACS, pep-ELISA, and WB applications and shows reactivity with Human samples.
The MA5-17188 immunogen is purified recombinant fragment of human THPO expressed in E. Coli.
MA5-17188 detects THPO which has a predicted molecular weight of approximately 37.8kDa.
Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Alternate splicing results in multiple transcript variants of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-mpl ligand; Megakaryocyte colony-stimulating factor; Megakaryocyte growth and development factor; megakaryocyte stimulating factor; MGDF; ML; MPL ligand; Myeloproliferative leukemia virus oncogene ligand; prepro-thrombopoietin; Thrombopoietin
Gene Aliases: MGDF; MKCSF; ML; MPLLG; THCYT1; THPO; TPO
UniProt ID: (Human) P40225
Entrez Gene ID: (Human) 7066