|Flow Cytometry (Flow)||4 µLx100 µL whole blood or 10^6 cells|
|Host / Isotype||Mouse / IgG1|
|Immunogen||anti-u-stimulated human B lymphocytes|
|Conjugate||Alexa Fluor® 647|
|Excitation/Emission Profile||View spectra|
|Storage buffer||PBS with 0.2% BSA|
|Contains||15mM sodium azide|
|Storage conditions||4° C, store in dark, DO NOT FREEZE!|
CD69 (AIM, Active Inducer Molecule) is a gp28/34 disulfide bonded homodimer with a molecular weight of 60 kDa under non-reducing conditions. CD69 contains one or two N linked oligosacaride and the molecule is present on activated platelets. In normal peripheral blood a variable percentage of cells express the CD69 antigen, and it is involved in lymphocyte signal transduction. Expression CD69 is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. Alternative splicing results in multiple transcript variants of CD69. Diseases associated with CD69 dysfunction include coccidiodomycosis and asthma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Activation inducer molecule; activation inducer molecule (AIM/CD69); AIM; BL-AC/P26; C-type lectin domain family 2; C-type lectin domain family 2 member C; C-type lectin domain family 2, member C; CD69; CD69 antigen; CD69 antigen (p60, early T-cell activation antigen); CLEC2C; EA1; Early activation antigen CD69; early lymphocyte activation antigen; Early T-cell activation antigen p60; GP32/28; Leukocyte surface antigen Leu-23; member C; MLR-3
Gene Aliases: AIM; BL-AC/P26; CD69; CLEC2C; EA1; GP32/28; MLR-3
UniProt ID: (Human) Q07108
Entrez Gene ID: (Human) 969
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