Peptide Sequence: LGFLSRLPPG PAGLDCSALD RDPDLQPPSG TSHFEFPDYC TPEVTEMIAG DWRPSSIADL VF
Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The protein encoded by this gene was identified as a SOX family member based on conserved domains, and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types.
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Protein Aliases: Protein SOX-22; SOX-22 protein; SRY (sex determining region Y)-box 12; SRY box 12; SRY-related HMG-box gene 22; Transcription factor SOX-12
Gene Aliases: SOX12; SOX22
UniProt ID: (Human) O15370
Entrez Gene ID: (Human) 6666